oleracein E

Base Information

Chemical Name:oleracein E
CAS No.:872100-58-8
Molecular Formula:C₁₂H₁₃NO₃
Molecular Weight:219.24
Hs Code.:

Synonyms:

Suppliers and Price of oleracein E

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of oleracein E

Chemical Property:

Purity/Quality:: ≥98% （HPLC） ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of oleracein E

There total 13 articles about oleracein E which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1344720-81-5
(10bR)-8-(2,2-dimethylpropanoyloxy)-9-methoxy-1,5,6,10b-tetrahydro-2H-pyrrolo[2,1-a]isoquinolin-3-one

: 872100-58-8,724706-17-6
oleracein E

Guidance literature:: (10bR)-8-(2,2-dimethylpropanoyloxy)-9-methoxy-1,5,6,10b-tetrahydro-2H-pyrrolo[2,1-a]isoquinolin-3-one; With boron tribromide; In dichloromethane; at 20 ℃; for 0.166667h; Inert atmosphere;

With water; In dichloromethane; Inert atmosphere;
DOI:10.1016/j.tet.2011.09.033

Reference yield:

: 222622-91-5
4-bromo-5-bromomethyl-2-methoxyphenol

: 872100-58-8,724706-17-6
oleracein E

Guidance literature:: Multi-step reaction with 11 steps

1.1: dimethyl sulfoxide / 0.08 h / 20 °C / Inert atmosphere

2.1: pyridine; dmap / dichloromethane / 20 h / 0 - 20 °C / Inert atmosphere

3.1: sodium tetrahydroborate; nickel(II) chloride hexahydrate / methanol / 1 h / 0 - 20 °C / Inert atmosphere

4.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium hydrogencarbonate / 1,4-dioxane; water / 2 h / 80 °C / Inert atmosphere

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 - 4 °C / Inert atmosphere

6.1: bismuth(lll) trifluoromethanesulfonate / dichloromethane / 1 h / -15 °C / Molecular sieve; Inert atmosphere

7.1: ozone / dichloromethane / 0.03 h / -78 °C

7.2: 0.25 h / 0 °C / Inert atmosphere

8.1: dichloromethane / 0.5 h / 20 °C / Inert atmosphere

9.1: palladium on activated charcoal; hydrogen / methanol / 12 h / 20 °C

10.1: trimethylsilyl trifluoromethanesulfonate; triethylamine / dichloromethane / 42 h / 20 °C / Inert atmosphere

11.1: boron tribromide / dichloromethane / 0.17 h / 20 °C / Inert atmosphere

11.2: Inert atmosphere

With bismuth(lll) trifluoromethanesulfonate; pyridine; dmap; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; nickel(II) chloride hexahydrate; trimethylsilyl trifluoromethanesulfonate; palladium on activated charcoal; tetrabutyl ammonium fluoride; hydrogen; boron tribromide; sodium hydrogencarbonate; ozone; triethylamine; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; dimethyl sulfoxide; 4.1: Suzuki-Miyaura coupling / 8.1: Wittig reaction;
DOI:10.1016/j.tet.2011.09.033

Reference yield:

: 1344720-62-2
2-bromo-5-(2,2-dimethylpropanoyloxy)-4-methoxy-phenyl-acetonitrile

: 872100-58-8,724706-17-6
oleracein E

Guidance literature:: Multi-step reaction with 9 steps

1.1: sodium tetrahydroborate; nickel(II) chloride hexahydrate / methanol / 1 h / 0 - 20 °C / Inert atmosphere

2.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium hydrogencarbonate / 1,4-dioxane; water / 2 h / 80 °C / Inert atmosphere

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 - 4 °C / Inert atmosphere

4.1: bismuth(lll) trifluoromethanesulfonate / dichloromethane / 1 h / -15 °C / Molecular sieve; Inert atmosphere

5.1: ozone / dichloromethane / 0.03 h / -78 °C

5.2: 0.25 h / 0 °C / Inert atmosphere

6.1: dichloromethane / 0.5 h / 20 °C / Inert atmosphere

7.1: palladium on activated charcoal; hydrogen / methanol / 12 h / 20 °C

8.1: trimethylsilyl trifluoromethanesulfonate; triethylamine / dichloromethane / 42 h / 20 °C / Inert atmosphere

9.1: boron tribromide / dichloromethane / 0.17 h / 20 °C / Inert atmosphere

9.2: Inert atmosphere

With bismuth(lll) trifluoromethanesulfonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; nickel(II) chloride hexahydrate; trimethylsilyl trifluoromethanesulfonate; palladium on activated charcoal; tetrabutyl ammonium fluoride; hydrogen; boron tribromide; sodium hydrogencarbonate; ozone; triethylamine; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; 2.1: Suzuki-Miyaura coupling / 6.1: Wittig reaction;
DOI:10.1016/j.tet.2011.09.033