trans-4'-(2-aminocyclopropyl)-(1,1'-biphenyl)-3-ol hydrochloride

Base Information

Chemical Name:trans-4'-(2-aminocyclopropyl)-(1,1'-biphenyl)-3-ol hydrochloride
CAS No.:1357298-75-9
Molecular Formula:C₁₅H₁₅NO*ClH
Molecular Weight:261.751
Hs Code.:

Synonyms:

Suppliers and Price of trans-4'-(2-aminocyclopropyl)-(1,1'-biphenyl)-3-ol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Axon Medchem
OG-L002hydrochloride 100%
25 mg
$ 467.50

Axon Medchem
OG-L002hydrochloride 100%
2 x 5 mg
$ 198.00

Axon Medchem
OG-L002hydrochloride 100%
5 mg
$ 137.50

Total 2 raw suppliers

Chemical Property of trans-4'-(2-aminocyclopropyl)-(1,1'-biphenyl)-3-ol hydrochloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

OG-L002hydrochloride 100% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of trans-4'-(2-aminocyclopropyl)-(1,1'-biphenyl)-3-ol hydrochloride

There total 3 articles about trans-4'-(2-aminocyclopropyl)-(1,1'-biphenyl)-3-ol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1418287-95-2
(±)-trans-O-tert-butyl-N-(2-(4-bromophenyl)cyclopropyl)carbamate

: 1357298-75-9
trans-4'-(2-aminocyclopropyl)-(1,1'-biphenyl)-3-ol hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; toluene; methanol / 18 h / 80 °C / Inert atmosphere

2: hydrogenchloride / water; tetrahydrofuran / 12 h / 20 °C

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In tetrahydrofuran; methanol; water; toluene; 1: |Suzuki-Miyaura Coupling;
DOI:10.1039/c6ob01483f

Reference yield:

: 1228092-84-9
(1R,2RS)-(-)-2-(4-bromophenyl)cyclopropyl-1-amine hydrochloride

: 1357298-75-9
trans-4'-(2-aminocyclopropyl)-(1,1'-biphenyl)-3-ol hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: dichloromethane / 3 h / 20 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; toluene; methanol / 18 h / 80 °C / Inert atmosphere

3: hydrogenchloride / water; tetrahydrofuran / 12 h / 20 °C

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In tetrahydrofuran; methanol; dichloromethane; water; toluene; 2: |Suzuki-Miyaura Coupling;
DOI:10.1039/c6ob01483f