Cefoxitin Impurity 6

Base Information

• Chemical Name: Cefoxitin Impurity 6
• CAS No.: 1422023-32-2
• Molecular Formula: C₁₆H₁₇N₃O₇S₂
• Molecular Weight: 427.459
• Mol file: 1422023-32-2.mol

Synonyms:

Chemical Property of Cefoxitin Impurity 6

Chemical Property:

• Melting Point: >94°C (dec.)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

≧95%, ^*data from raw suppliers

Δ2-Cefoxitin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Δ2-Cefoxitin is a derivative of Cefoxitin (C243200), a semi-synthetic antibiotic derived from Cephamycin C, possessing high resistance to β-lactamase inactivation. An antibacterial.

Technology Process of Cefoxitin Impurity 6

There total 2 articles about Cefoxitin Impurity 6 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

cefoxitin (35607-66-0) → (2R,6R,7S)-3-((carbamoyloxy)methyl)-7-methoxy-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid (1422023-32-2)

Guidance literature:

With triethylamine; In methanol; at 20 ℃; for 24h;

DOI:10.3184/174751918X15402956899595

Reference yield:

→ Cefoxitin (1422023-32-2)

Guidance literature:

Hydroxyverb. 4b, 1) Trichloracetylisocyanat, 2) MeOH/K2CO3, 3) MCPBA-=m-Chlorper-benzoesaeure, 4) PCl3/CH3CON(CH3)2, 5) LiOMe/Bu-hypochlorit, 6) F3CCO2H;

DOI:10.1016/S0040-4039(01)88973-5

upstream raw materials:

cefoxitin