3-bromo-5-isopropylphenol

Base Information

• Chemical Name: 3-bromo-5-isopropylphenol
• CAS No.: 1243475-87-7
• Molecular Formula: C₉H₁₁BrO
• Molecular Weight: 215.09
• Mol file: 1243475-87-7.mol

Synonyms:

Chemical Property of 3-bromo-5-isopropylphenol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

3-Bromo-5-isopropylphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-bromo-5-isopropylphenol

There total 2 articles about 3-bromo-5-isopropylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(3-bromo-5-isopropylphenyl)boronic acid (1451390-87-6) → 3-bromo-5-isopropylphenol (1243475-87-7)

Guidance literature:

With dihydrogen peroxide; In water; at 20 ℃; for 2h;

DOI:10.1124/jpet.117.240721

Reference yield: 70.0%

2-diazo-5-isopropyl-cyclohexane-1,3-dione → 3-bromo-5-isopropylphenol (1243475-87-7)

Guidance literature:

With tris(triphenylphosphine)ruthenium(II) chloride; Oxalyl bromide; In fluorobenzene; at 20 ℃; for 10h; Inert atmosphere;

DOI:10.1002/adsc.201400348

upstream raw materials:

(3-bromo-5-isopropylphenyl)boronic acid

Refernces

• 1、 Kiser, Philip D.,Zhang, Jianye,Palczewski, Krzysztof,Badiee, Mohsen,Tochtrop, Gregory P.,Peachey, Neal S.,Kinoshita, Junzo. "Rational tuning of visual cycle modulator pharmacodynamics". . p. 131 - 145. Retrieved 2017/06/29.