(5-Fluoroquinolin-8-yl)methanol

Base Information

• Chemical Name: (5-Fluoroquinolin-8-yl)methanol
• CAS No.: 1153758-16-7
• Molecular Formula: C₁₀H₈FNO
• Molecular Weight: 177.178
• DSSTox Substance ID: DTXSID80656180
• Wikidata: Q82570714
• Mol file: 1153758-16-7.mol

Synonyms:(5-fluoroquinolin-8-yl)methanol;1153758-16-7;DTXSID80656180;AKOS009590095;SB68248;CS-0216709;EN300-55364;Z431952904

Chemical Property of (5-Fluoroquinolin-8-yl)methanol

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 177.058992041
• Heavy Atom Count: 13
• Complexity: 176

Purity/Quality:

98.5% ^*data from raw suppliers

(5-Fluoroquinolin-8-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC2=C(C=CC(=C2N=C1)CO)F

Technology Process of (5-Fluoroquinolin-8-yl)methanol

There total 2 articles about (5-Fluoroquinolin-8-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C25H23FN3O3PdS (1063398-62-8,1064661-80-8) + acetic anhydride (108-24-7) → (5-fluoroquinolin-8-yl)methyl acetate + C10H8FNO (1153758-16-7)

Guidance literature:

With oxygen; In acetic acid; at 60 ℃; Inert atmosphere;

DOI:10.1039/b803156h

Reference yield:

C17H11FN2O5Pd + acetic anhydride (108-24-7) → (5-fluoroquinolin-8-yl)methyl acetate + C10H8FNO (1153758-16-7)

Guidance literature:

With oxygen; In acetic acid; at 60 ℃; for 5h; Inert atmosphere;

DOI:10.1039/b803156h

upstream raw materials:

C₂₅H₂₃FN₃O₃PdS

acetic anhydride