L-piperidine-2-carbonyl-L-leucylglycinamide hydrochloride

Base Information

Chemical Name:L-piperidine-2-carbonyl-L-leucylglycinamide hydrochloride
CAS No.:16295-99-1
Molecular Formula:C₁₄H₂₆N₄O₃*ClH
Molecular Weight:334.846
Hs Code.:

Synonyms:

Suppliers and Price of L-piperidine-2-carbonyl-L-leucylglycinamide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of L-piperidine-2-carbonyl-L-leucylglycinamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of L-piperidine-2-carbonyl-L-leucylglycinamide hydrochloride

There total 4 articles about L-piperidine-2-carbonyl-L-leucylglycinamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 103225-09-8
Boc-Pip-Leu-Gly-NH2

: 16295-99-1
L-piperidine-2-carbonyl-L-leucylglycinamide hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; for 0.75h; Ambient temperature;
DOI:10.1021/jm00160a052

Reference yield:

: 26250-84-0
(S)-(-)-1-(tert-butoxycarbonyl)-2-piperidinecarboxylic acid

: 16295-99-1
L-piperidine-2-carbonyl-L-leucylglycinamide hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) N-methylmorpholine, isobutylchloroformate, 2.) Et₃N / 1.) THF, -20 deg C, 10 min, 2.) THF, DMF, H₂O, RT, 1 h

2: 67 percent / 4 N aq. HCl / dioxane / 0.75 h / Ambient temperature

With 4-methyl-morpholine; hydrogenchloride; triethylamine; isobutyl chloroformate; In 1,4-dioxane;
DOI:10.1021/jm00160a052

Reference yield:

: 38173-66-9
HCl_.H-Leu-Gly-NH₂

: 16295-99-1
L-piperidine-2-carbonyl-L-leucylglycinamide hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) N-methylmorpholine, isobutylchloroformate, 2.) Et₃N / 1.) THF, -20 deg C, 10 min, 2.) THF, DMF, H₂O, RT, 1 h

2: 67 percent / 4 N aq. HCl / dioxane / 0.75 h / Ambient temperature

With 4-methyl-morpholine; hydrogenchloride; triethylamine; isobutyl chloroformate; In 1,4-dioxane;
DOI:10.1021/jm00160a052