Technology Process of C14H16BrNO4
There total 1 articles about C14H16BrNO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(3-Bromophenyl)methanol;
With
pyridine; 4-Nitrophenyl chloroformate;
In
dichloromethane;
for 18h;
methyl (2S)-pyrrolidine carboxylate;
With
4-methyl-morpholine;
In
tetrahydrofuran; acetonitrile;
for 3h;
Reflux;
DOI:10.1016/j.bmcl.2014.04.002
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium hydroxide; water / methanol; tetrahydrofuran
1.2: 18 h
1.3: 3 h
2.1: lithium hydroxide; water / tetrahydrofuran
2.2: 18 h
3.1: sodium carbonate / N,N-dimethyl-formamide; water / 60 °C
With
water; sodium carbonate; lithium hydroxide;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2014.04.002
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium hydroxide; water / methanol; tetrahydrofuran
1.2: 18 h
1.3: 3 h
2.1: lithium hydroxide; water / tetrahydrofuran
2.2: 18 h
With
water; lithium hydroxide;
In
tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2014.04.002