4-chloro-6-methoxy-2-(propylthio)pyrimidin-5-amine

Base Information

Chemical Name:4-chloro-6-methoxy-2-(propylthio)pyrimidin-5-amine
CAS No.:1431867-40-1
Molecular Formula:C₈H₁₂ClN₃OS
Molecular Weight:233.722
Hs Code.:

Synonyms:

Suppliers and Price of 4-chloro-6-methoxy-2-(propylthio)pyrimidin-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
4-Chloro-6-methoxy-2-propylsulfanylpyrimidin-5-amine
2mg
$ 255.00

TRC
4-Chloro-6-methoxy-2-(propylthio)-5-pyrimidinamine
25mg
$ 695.00

Total 5 raw suppliers

Chemical Property of 4-chloro-6-methoxy-2-(propylthio)pyrimidin-5-amine

Chemical Property:

Purity/Quality:

>95% ^*data from raw suppliers

4-Chloro-6-methoxy-2-propylsulfanylpyrimidin-5-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4-Chloro-6-methoxy-2-(propylthio)-5-pyrimidinamine is an intermediate used in the syntehsis of ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist.

Technology Process of 4-chloro-6-methoxy-2-(propylthio)pyrimidin-5-amine

There total 2 articles about 4-chloro-6-methoxy-2-(propylthio)pyrimidin-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1431867-39-8
4-chloro-6-methoxy-5-nitro-2-(propylthio)pyrimidine

: 1431867-40-1
4-chloro-6-methoxy-2-(propylthio)pyrimidin-5-amine

Guidance literature:: With iron; acetic acid; at 20 ℃; for 2h;

Reference yield:

: 145783-14-8
4,6-dichloro-5-nitro-2-(propylsulfanyl)pyrimidine

: 1431867-40-1
4-chloro-6-methoxy-2-(propylthio)pyrimidin-5-amine

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 1 h / 20 °C

2: iron; acetic acid / 2 h / 20 °C

With iron; acetic acid; In methanol;