Papuamine

Base Information

Chemical Name:Papuamine
CAS No.:112455-84-2
Molecular Formula:C₂₅H₄₀N₂
Molecular Weight:368.606
Hs Code.:
UNII:6695RBD96K
DSSTox Substance ID:DTXSID301019061
Nikkaji Number:J819.991D
Wikidata:Q27263982
Metabolomics Workbench ID:132033
ChEMBL ID:CHEMBL3577062

Synonyms:papuamine

Suppliers and Price of Papuamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Papuamine
100μg
$ 290.00

Total 2 raw suppliers

Chemical Property of Papuamine

Chemical Property:

Melting Point:167.5-169°
XLogP3:6.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:368.319149284
Heavy Atom Count:27
Complexity:505

Purity/Quality:

97% ^*data from raw suppliers

Papuamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC2C(C1)CC3C2C=CC=CC4C5CCCCC5CC4NCCCN3
Isomeric SMILES:C1C[C@@H]2[C@H]([C@H]\3[C@@H](C2)NCCCN[C@H]4[C@H]([C@H]5[C@H](C4)CCCC5)/C=C/C=C3)CC1
Uses Papuamine is a pentacyclic alkaloid and antifungal agent.

Technology Process of Papuamine

There total 15 articles about Papuamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: C₂₇H₃₈F₆N₂O₄S₂

: 112455-84-2,117065-24-4
haliclonadiamine

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at 70 ℃; for 96h;
DOI:10.1021/ja962162u

Reference yield:

: {(1S,2R)-2-[3-(Dimethyl-phenyl-silanyl)-propa-1,2-dienyl]-cyclohexyl}-acetaldehyde

: 112455-84-2,117065-24-4
papuamine

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / toluene / 16 h / Heating

2: 1.) Bu₃SnH, AIBN, 2.) PdCl₂(PPh₃)2, O₂ / 1.) THF, reflux, 2.) DMF, RT

With bis-triphenylphosphine-palladium(II) chloride; 2,2'-azobis(isobutyronitrile); oxygen; tri-n-butyl-tin hydride; In toluene;
DOI:10.1021/ja00100a070

Reference yield:

: {(1S,2R)-2-[3-(Dimethyl-phenyl-silanyl)-propa-1,2-dienyl]-cyclohexyl}-acetonitrile

: 112455-84-2,117065-24-4
papuamine

Guidance literature:: Multi-step reaction with 3 steps

1: DibalH / toluene / -78 - 0 °C

2: 70 percent / toluene / 16 h / Heating

3: 1.) Bu₃SnH, AIBN, 2.) PdCl₂(PPh₃)2, O₂ / 1.) THF, reflux, 2.) DMF, RT

With bis-triphenylphosphine-palladium(II) chloride; 2,2'-azobis(isobutyronitrile); oxygen; tri-n-butyl-tin hydride; diisobutylaluminium hydride; In toluene;
DOI:10.1021/ja00100a070