3-(m-tolyloxy)pyrrolidine

Base Information

• Chemical Name: 3-(m-tolyloxy)pyrrolidine
• CAS No.: 1017803-19-8
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.246
• Mol file: 1017803-19-8.mol

Synonyms:

Chemical Property of 3-(m-tolyloxy)pyrrolidine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

(R)-3-(3-Methylphenoxy)pyrrolidine HCl 95+% ee ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(m-tolyloxy)pyrrolidine

There total 2 articles about 3-(m-tolyloxy)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methyl-phenol (108-39-4) + tert-butyl (3R)-3-methylsulfonyloxypyrrolidine-1-carboxylate (127423-61-4) → (S)-3-m-tolyloxy-pyrrolidine (1017803-19-8)

Guidance literature:

3-methyl-phenol; tert-butyl (3R)-3-methylsulfonyloxypyrrolidine-1-carboxylate; With sodium hydride; In N,N-dimethyl-formamide; at 60 ℃;

With hydrogenchloride; Further stages.;

DOI:10.1080/00397910701796691

Reference yield:

→ 3-(m-tolyloxy)pyrrolidine (946726-81-4,1017803-19-8)

Guidance literature:

upstream raw materials:

3-methyl-phenol

tert-butyl (3R)-3-methylsulfonyloxypyrrolidine-1-carboxylate