23R,25-dihydroxyvitamin D₃

Base Information

Chemical Name:23R,25-dihydroxyvitamin D₃
CAS No.:81738-09-2
Molecular Formula:C₂₇H₄₄O₃
Molecular Weight:416.645
Hs Code.:

Synonyms:

Suppliers and Price of 23R,25-dihydroxyvitamin D₃

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(23R)-23,25-Dihydroxyvitamin D3
5mg
$ 1980.00

TRC
(23R)-23,25-Dihydroxyvitamin D3
2.5mg
$ 1045.00

Sigma-Aldrich
(23R)-23,25-Dihydroxyvitamin D3 ≥99.0% (HPLC)
100ug
$ 171.00

Total 4 raw suppliers

Chemical Property of 23R,25-dihydroxyvitamin D₃

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

(23R)-23,25-Dihydroxyvitamin D3 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (23R)-23,25-Dihydroxyvitamin D3 is a vitamin D3 metabolite found in humans. able to increase the plasma lactone concentration

Technology Process of 23R,25-dihydroxyvitamin D₃

There total 20 articles about 23R,25-dihydroxyvitamin D₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₇H₆₂O₅Si

: 81738-09-2
23(S),25-dihydroxy-24-oxovitamin D₃

Guidance literature:: C₃₇H₆₂O₅Si; With toluene-4-sulfonic acid; In methanol; at 20 ℃;

With potassium carbonate; In methanol; at 20 ℃;
DOI:10.1002/cbic.202100250

Reference yield:

: C₃₇H₆₂O₅Si

: 81738-09-2
23R,25-dihydroxyvitamin D₃

Guidance literature:: C₃₇H₆₂O₅Si; With toluene-4-sulfonic acid; In methanol; at 20 ℃;

With potassium carbonate; In methanol; at 20 ℃;
DOI:10.1002/cbic.202100250

Reference yield:

: 93489-71-5
(R)-3-((1R,3aR,4S,7aR)-4-((tert-butyldimethylsilyl)oxy)-7a-methyloctahydro-1H-inden-1-yl)butanal

: 81738-09-2
23R,25-dihydroxyvitamin D₃

Guidance literature:: Multi-step reaction with 7 steps

1.1: indium / tetrahydrofuran / 0 °C / Sonication

2.1: tetrahydrofuran / 0 °C

3.1: triethylamine; dmap / dichloromethane / Reflux

4.1: water; hydrogen fluoride / dichloromethane; acetonitrile / 20 °C

5.1: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / dichloromethane / 20 °C / Molecular sieve

6.1: n-butyllithium / tetrahydrofuran / -78 °C

7.1: toluene-4-sulfonic acid / methanol / 20 °C

7.2: 20 °C

With dmap; indium; n-butyllithium; tetrapropylammonium perruthennate; hydrogen fluoride; water; toluene-4-sulfonic acid; 4-methylmorpholine N-oxide; triethylamine; In tetrahydrofuran; methanol; dichloromethane; acetonitrile; 6.1: |Wittig Olefination;
DOI:10.1002/cbic.202100250