Technology Process of 3-bromo-4-(3-methyloxetan-3-yl)aniline
There total 3 articles about 3-bromo-4-(3-methyloxetan-3-yl)aniline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.22 h / 0 - 20 °C / Inert atmosphere
1.2: 0.17 h / 20 °C / Inert atmosphere
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere
3.1: cyanomethylenetributyl-phosphorane / benzene / 72 h / 20 °C
4.1: tin(II) chloride dihdyrate / ethanol / 1 h / 70 °C
With
lithium aluminium tetrahydride; tin(II) chloride dihdyrate; sodium hydride; cyanomethylenetributyl-phosphorane;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; mineral oil; benzene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere
2: cyanomethylenetributyl-phosphorane / benzene / 72 h / 20 °C
3: tin(II) chloride dihdyrate / ethanol / 1 h / 70 °C
With
lithium aluminium tetrahydride; tin(II) chloride dihdyrate; cyanomethylenetributyl-phosphorane;
In
tetrahydrofuran; ethanol; benzene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: cyanomethylenetributyl-phosphorane / benzene / 72 h / 20 °C
2: tin(II) chloride dihdyrate / ethanol / 1 h / 70 °C
With
tin(II) chloride dihdyrate; cyanomethylenetributyl-phosphorane;
In
ethanol; benzene;