C₁₈H₁₈S

Base Information

• Chemical Name: C₁₈H₁₈S
• CAS No.: 74498-50-3
• Molecular Formula: C₁₈H₁₈S
• Molecular Weight: 266.407
• Mol file: 74498-50-3.mol

Synonyms:

Chemical Property of C₁₈H₁₈S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₁₈S

There total 8 articles about C₁₈H₁₈S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

pseudogem-Bis(bromomethyl)<2.2>paracyclophane (43045-00-7) → C18H18S (74498-50-3)

Guidance literature:

With 1,2-bis(mercaptomethyl)benzene; potassium hydroxide; In ethanol; benzene; Reagent/catalyst;

DOI:10.1139/cjc-2016-0358

Reference yield: 60.0%

pseudogem-Bis(bromomethyl)<2.2>paracyclophane (43045-00-7) + 4,15-bis(mercaptomethyl)[2.2]paracyclophane → C36H36S2 + C18H18S (74498-50-3)

Guidance literature:

With cesium hydroxide; In ethanol; benzene;

DOI:10.1139/cjc-2016-0358

Reference yield:

[2.2]Paracyclophan (1633-22-3) → C18H18S (74498-50-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 74 percent / Aluminum chloride / CH₂Cl₂ / 0.25 h / -50 - -20 °C

2: 55 percent / Hydrochloric acid / 3.75 h / 55 °C

3: KOH, Bromine / dioxane / 17 h / Ambient temperature

4: 72 percent / Lithium aluminum hydride / tetrahydrofuran / 96 h / Heating

5: 81 percent / Phosphorus tribromide / CH₂Cl₂ / 0.5 h / -20 °C

6: 39 percent / Sodium sulfide / ethanol / 8 h / Ambient temperature

With hydrogenchloride; sodium sulfide; potassium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; bromine; phosphorus tribromide; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane;

DOI:10.1021/jo01308a005

upstream raw materials:

pseudogem-Bis(bromomethyl)<2.2>paracyclophane

[2.2]Paracyclophan

4-acetyl[2.2]paracyclophane

pseudogem-Acetyl(chloromethyl)<2.2>paracyclophane