AMINO-(3,5-DIMETHYL-PHENYL)-ACETIC ACID

Base Information

• Chemical Name: AMINO-(3,5-DIMETHYL-PHENYL)-ACETIC ACID
• CAS No.: 199327-17-8
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.219
• Mol file: 199327-17-8.mol

Synonyms:

Chemical Property of AMINO-(3,5-DIMETHYL-PHENYL)-ACETIC ACID

Chemical Property:

• Boiling Point: 317.1±30.0 °C(Predicted)
• PKA: 1.95±0.10(Predicted)
• Density: 1.164±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Amino-(3,5-dimethyl-phenyl)-aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of AMINO-(3,5-DIMETHYL-PHENYL)-ACETIC ACID

There total 2 articles about AMINO-(3,5-DIMETHYL-PHENYL)-ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(R)-N-(trifluoroacetyl)-2-(3,5-dimethylphenyl)glycine (338731-86-5) → (R)-N-2-(3,5-dimethylphenyl)glycine (199327-17-8)

Guidance literature:

With hydrogenchloride; for 1h; Heating;

DOI:10.1248/cpb.49.330

Reference yield:

(RS)-3,5-dimethylphenylglycine (199327-17-8) → (R)-N-2-(3,5-dimethylphenyl)glycine (199327-17-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Et₃N / methanol / 24 h / 20 °C

1.2: racemate resolution via salt with cinchonine

2.1: 80 percent / aq. HCl / 1 h / Heating

With hydrogenchloride; triethylamine; In methanol;

DOI:10.1248/cpb.49.330

upstream raw materials:

(R)-N-(trifluoroacetyl)-2-(3,5-dimethylphenyl)glycine

Refernces