(2S,3S)-1,4-Dioxa-spiro[4.5]decane-2,3-dicarboxylic acid methyl ester (1R,2S,3S,4R,5S,6R)-2,4,6-tris-benzoyloxy-3,5-bis-benzyloxy-cyclohexyl ester

Base Information

• Chemical Name: (2S,3S)-1,4-Dioxa-spiro[4.5]decane-2,3-dicarboxylic acid methyl ester (1R,2S,3S,4R,5S,6R)-2,4,6-tris-benzoyloxy-3,5-bis-benzyloxy-cyclohexyl ester
• CAS No.: 132741-45-8
• Molecular Formula: C₅₂H₅₀O₁₄
• Molecular Weight: 898.961
• Mol file: 132741-45-8.mol

Synonyms:

Chemical Property of (2S,3S)-1,4-Dioxa-spiro[4.5]decane-2,3-dicarboxylic acid methyl ester (1R,2S,3S,4R,5S,6R)-2,4,6-tris-benzoyloxy-3,5-bis-benzyloxy-cyclohexyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3S)-1,4-Dioxa-spiro[4.5]decane-2,3-dicarboxylic acid methyl ester (1R,2S,3S,4R,5S,6R)-2,4,6-tris-benzoyloxy-3,5-bis-benzyloxy-cyclohexyl ester

There total 1 articles about (2S,3S)-1,4-Dioxa-spiro[4.5]decane-2,3-dicarboxylic acid methyl ester (1R,2S,3S,4R,5S,6R)-2,4,6-tris-benzoyloxy-3,5-bis-benzyloxy-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-benzyl 2,2,2-trichloroacetimidate (81927-55-1) + (2S,3S)-1,4-Dioxa-spiro[4.5]decane-2,3-dicarboxylic acid methyl ester (1R,2S,3S,4R,5S,6R)-2,4,6-tris-benzoyloxy-3,5-dihydroxy-cyclohexyl ester (130515-77-4,130607-69-1) → (2S,3S)-1,4-Dioxa-spiro[4.5]decane-2,3-dicarboxylic acid methyl ester (1R,2S,3S,4R,5S,6R)-2,4,6-tris-benzoyloxy-3,5-bis-benzyloxy-cyclohexyl ester (132741-45-8)

Guidance literature:

With trifluorormethanesulfonic acid;

DOI:10.1016/0040-4039(90)80139-D

Reference yield:

(2S,3S)-1,4-Dioxa-spiro[4.5]decane-2,3-dicarboxylic acid methyl ester (1R,2S,3S,4R,5S,6R)-2,4,6-tris-benzoyloxy-3,5-bis-benzyloxy-cyclohexyl ester (132741-45-8) → (-)-1L-2,6-di-O-benzyl-myo-inositol (115015-97-9,1214834-30-6)

Guidance literature:

With sodium methylate;

DOI:10.1016/0040-4039(90)80139-D

upstream raw materials:

O-benzyl 2,2,2-trichloroacetimidate

(2S,3S)-1,4-Dioxa-spiro[4.5]decane-2,3-dicarboxylic acid methyl ester (1R,2S,3S,4R,5S,6R)-2,4,6-tris-benzoyloxy-3,5-dihydroxy-cyclohexyl ester

Downstream raw materials:

(-)-1L-2,6-di-O-benzyl-myo-inositol