(S)-Benzyl tert-butyl (2-hydroxyethane-1,1-diyl)dicarbamate

Base Information

Chemical Name:(S)-Benzyl tert-butyl (2-hydroxyethane-1,1-diyl)dicarbamate
CAS No.:306773-86-4
Molecular Formula:C₁₅H₂₂N₂O₅
Molecular Weight:310.35
Hs Code.:
DSSTox Substance ID:DTXSID001115626
Nikkaji Number:J1.475.969G
Mol file:306773-86-4.mol

Synonyms:306773-86-4;(S)-Benzyl tert-butyl (2-hydroxyethane-1,1-diyl)dicarbamate;benzyl N-[(1S)-2-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonylamino]ethyl]carbamate;DTXSID001115626;MFCD28991930;W11235;(S)-Benzyltert-butyl(2-hydroxyethane-1,1-diyl)dicarbamate;(S)-2-(tert-Butyloxycarbonylamino)-2-(benzyloxycarbonylamino)ethanol;Carbamic acid, [(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxyethyl]-, phenylmethyl ester

Suppliers and Price of (S)-Benzyl tert-butyl (2-hydroxyethane-1,1-diyl)dicarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-Benzyltert-butyl(2-hydroxyethane-1,1-diyl)dicarbamate 95+%
5g
$ 1786.00

Crysdot
(S)-Benzyltert-butyl(2-hydroxyethane-1,1-diyl)dicarbamate 95+%
1g
$ 594.00

Total 1 raw suppliers

Chemical Property of (S)-Benzyl tert-butyl (2-hydroxyethane-1,1-diyl)dicarbamate

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:310.15287181
Heavy Atom Count:22
Complexity:361

Purity/Quality:: (S)-Benzyltert-butyl(2-hydroxyethane-1,1-diyl)dicarbamate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CO)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CO)NC(=O)OCC1=CC=CC=C1

Technology Process of (S)-Benzyl tert-butyl (2-hydroxyethane-1,1-diyl)dicarbamate

There total 5 articles about (S)-Benzyl tert-butyl (2-hydroxyethane-1,1-diyl)dicarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 306773-79-5
(R)-4-benzyloxycarbonylamino-3-tert-butoxycarbonyl-2-oxazolidone

: 306773-80-8,306773-86-4
(R)-2-hydroxy-1-tert-butoxycarbonylaminoethylcarbamic acid benzyl ester

Guidance literature:: With N-benzyl-trimethylammonium hydroxide; In tetrahydrofuran; methanol; at -40 ℃; for 0.666667h;
DOI:10.1021/jo000736e

Reference yield: 68.0%

: 306773-85-3
(S)-3-benzyloxycarbonylamino-4-tert-butoxycarbonylamino-2-oxazolidone

: 306773-86-4
(S)-2-hydroxy-1-tert-butoxycarbonylaminoethylcarbamic acid benzyl ester

Guidance literature:: With N-benzyl-trimethylammonium hydroxide; In methanol; toluene; at -45 ℃; for 0.75h;
DOI:10.1021/jo000736e

Reference yield:

: 82933-44-6
2-oxooxazolidin-4-ylcarbamic acid tert-butyl ester

: 306773-86-4
(S)-2-hydroxy-1-tert-butoxycarbonylaminoethylcarbamic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / Et₃N / tetrahydrofuran / -40 - -15 °C

2: 68 percent / benzyltrimethylammonium hydroxide / toluene; methanol / 0.75 h / -45 °C

With N-benzyl-trimethylammonium hydroxide; triethylamine; In tetrahydrofuran; methanol; toluene; 1: Substitution / 2: Ring cleavage;
DOI:10.1021/jo000736e