1-((Methoxycarbonyl)amino)cyclopentane-1-carboxylic acid

Base Information

Chemical Name:1-((Methoxycarbonyl)amino)cyclopentane-1-carboxylic acid
CAS No.:6949-76-4
Molecular Formula:C8H13 N O4
Molecular Weight:187.1931
Hs Code.:
NSC Number:22848
DSSTox Substance ID:DTXSID80281739
Wikidata:Q82015796
ChEMBL ID:CHEMBL1873759

Synonyms:6949-76-4;1-((methoxycarbonyl)amino)cyclopentane-1-carboxylic acid;MLS000738008;1-(methoxycarbonylamino)cyclopentane-1-carboxylic acid;1-[(methoxycarbonyl)amino]cyclopentane-1-carboxylic acid;Cyclopentanecarboxylicacid, 1-[(methoxycarbonyl)amino]-;1-((Methoxycarbonyl)amino)cyclopentanecarboxylic acid;NSC22848;SCHEMBL755311;CHEMBL1873759;DTXSID80281739;HMS2747A14;MFCD11212138;NSC 22848;NSC-22848;AKOS009343272;AS-43763;SMR000393685;CS-0133656;EN300-69515;1-((Methoxycarbonyl)amino)cyclopentanecarboxylicacid;Z385442970

Suppliers and Price of 1-((Methoxycarbonyl)amino)cyclopentane-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-((Methoxycarbonyl)amino)cyclopentane-1-carboxylic acid

Chemical Property:

Vapor Pressure:3.86E-06mmHg at 25°C
Boiling Point:359.4°C at 760 mmHg
Flash Point:171.2°C
Density:1.25g/cm³
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:187.08445790
Heavy Atom Count:13
Complexity:220

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)NC1(CCCC1)C(=O)O

Technology Process of 1-((Methoxycarbonyl)amino)cyclopentane-1-carboxylic acid

There total 8 articles about 1-((Methoxycarbonyl)amino)cyclopentane-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 79-22-1
methyl chloroformate

: 52-52-8
1-amino-1-cyclopentanecarboxylic acid

: 6949-76-4
1-((methoxycarbonyl)amino)cyclopentane-1-carboxylic acid

Guidance literature:: With sodium carbonate; sodium hydroxide; In 1,4-dioxane; at 0 - 20 ℃;
DOI:10.1021/acs.jmedchem.0c00529

Reference yield: 64.0%

: methyl (1-vinylcyclopentyl)carbamate

: 6949-76-4
1-((methoxycarbonyl)amino)cyclopentane-1-carboxylic acid

Guidance literature:: methyl (1-vinylcyclopentyl)carbamate; With ozone; In dichloromethane; at -78 ℃;

With sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; In water; tert-butyl alcohol;
DOI:10.1021/acs.joc.5b02628

Reference yield:

: 1903-22-6
ethyl cyclopentylideneacetate

: 6949-76-4
1-((methoxycarbonyl)amino)cyclopentane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: diisobutylaluminium hydride / hexane; dichloromethane / -70 °C

2.1: dichloromethane / 1 h / -10 - 20 °C

2.2: 1.5 h

3.1: triethylamine; trifluoroacetic anhydride / tetrahydrofuran / 1 h / 0 - 20 °C

4.1: methanol; tetrahydrofuran / 20 °C

5.1: ozone / dichloromethane / -78 °C

With diisobutylaluminium hydride; ozone; triethylamine; trifluoroacetic anhydride; In tetrahydrofuran; methanol; hexane; dichloromethane;
DOI:10.1021/acs.joc.5b02628