2-chloro-3,5,6-triphenylpyrazine

Base Information

• Chemical Name: 2-chloro-3,5,6-triphenylpyrazine
• CAS No.: 243472-78-8
• Molecular Formula: C₂₂H₁₅ClN₂
• Molecular Weight: 342.827
• Mol file: 243472-78-8.mol

Synonyms:

Chemical Property of 2-chloro-3,5,6-triphenylpyrazine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-chloro-3,5,6-triphenylpyrazine

There total 2 articles about 2-chloro-3,5,6-triphenylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,5-triphenyl-6-trimethylsilanyloxy-pyrazine (243472-86-8) → 2-chloro-3,5,6-triphenylpyrazine (243472-78-8)

Guidance literature:

With phosphorus pentachloride; Yield given; Heating;

DOI:10.1002/jhet.5570360334

Reference yield:

3,5,6-triphenyl-pyrazin-2-ol → 2-chloro-3,5,6-triphenylpyrazine (243472-78-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Me₃SiCl / 0.5 h / Heating

2: PCl₅ / Heating

With chloro-trimethyl-silane; phosphorus pentachloride;

DOI:10.1002/jhet.5570360334

upstream raw materials:

2,3,5-triphenyl-6-trimethylsilanyloxy-pyrazine

Refernces