cis-tetrahydro-thiophene-2,5-dicarboxylic acid diamide

Base Information

• Chemical Name: cis-tetrahydro-thiophene-2,5-dicarboxylic acid diamide
• CAS No.: 98484-56-1
• Molecular Formula: C₆H₁₀N₂O₂S
• Molecular Weight: 174.224
• Mol file: 98484-56-1.mol

Synonyms:

Chemical Property of cis-tetrahydro-thiophene-2,5-dicarboxylic acid diamide

Chemical Property:

Purity/Quality:

Tetrahydrothiophene-2,5-dicarboxamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-tetrahydro-thiophene-2,5-dicarboxylic acid diamide

There total 3 articles about cis-tetrahydro-thiophene-2,5-dicarboxylic acid diamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cis-tetrahydro-thiophene-2,5-dicarboxylic acid diethyl ester (54732-78-4) → cis-tetrahydro-thiophene-2,5-dicarboxylic acid diamide (98484-56-1)

Guidance literature:

With methanol; sodium methylate; anschliessend Behandeln mit wss. Ammoniak;

DOI:10.1021/jo01155a020

Reference yield:

diethyl meso-2,5-dibromoadipate (54221-37-3) → cis-tetrahydro-thiophene-2,5-dicarboxylic acid diamide (98484-56-1)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium iodide; ethanol; sodium sulfide

2: sodium methylate; methanol / anschliessend Behandeln mit wss. Ammoniak

With methanol; sodium sulfide; ethanol; sodium methylate; potassium iodide;

DOI:10.1021/jo01155a020

Reference yield:

→ cis-tetrahydro-thiophene-2,5-dicarboxylic acid diamide (98484-56-1)

Guidance literature:

With diethyl ether; ammonia;

upstream raw materials:

cis-tetrahydro-thiophene-2,5-dicarboxylic acid diethyl ester

diethyl meso-2,5-dibromoadipate