C₁₆H₂₃NO₄Se

Base Information

• Chemical Name: C₁₆H₂₃NO₄Se
• CAS No.: 2044711-02-4
• Molecular Formula: C₁₆H₂₃NO₄Se
• Molecular Weight: 372.323
• Mol file: 2044711-02-4.mol

Synonyms:

Chemical Property of C₁₆H₂₃NO₄Se

Chemical Property:

• Boiling Point: 515.1±50.0 °C(Predicted)

Purity/Quality:

HPLC>98% ^*data from raw suppliers

Boc-D-Sec(pMeBzl)-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₂₃NO₄Se

There total 18 articles about C₁₆H₂₃NO₄Se which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-tert-butoxycarbonylamino-3-(4-methyl-benzylselanyl)-propionic acid methyl ester (922178-77-6) → N-Boc-L-Sec(4-MeBzl)-OH (869646-27-5,2044711-02-4)

Guidance literature:

With trimethyltin hydroxide; In 1,2-dichloro-ethane; at 80 ℃; for 3h;

DOI:10.1021/ja0661414

Reference yield:

C17H25NO4Se → C16H23NO4Se (869646-27-5,2044711-02-4)

Guidance literature:

With trimethyltin(IV) hydroxide; In 1,2-dichloro-ethane; at 80 ℃; for 2h;

DOI:10.3998/ark.5550190.p009.803

Reference yield:

(S)-N-(tert-butoxycarbonyl)serine (3262-72-4) → N-Boc-L-Sec(4-MeBzl)-OH (869646-27-5,2044711-02-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 85 percent / K₂CO₃ / dimethylformamide

2: 85 percent / pyridine

3: 64 percent / NaOH / acetone; H₂O; dimethylformamide / 4 h / 0 °C

4: 95 percent / trimethyltin hydroxide / 1,2-dichloro-ethane / 3 h / 80 °C

With pyridine; sodium hydroxide; trimethyltin hydroxide; potassium carbonate; In water; 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetone;

DOI:10.1021/ja0661414

upstream raw materials:

2-tert-butoxycarbonylamino-3-(4-methyl-benzylselanyl)-propionic acid methyl ester

p-tolyl-methaneselenol

(S)-N-(tert-butoxycarbonyl)serine

bis-4-(methylbenzyl)-diselenide