1-(3-Chloropyridin-4-yl)piperazine

Base Information

Chemical Name:1-(3-Chloropyridin-4-yl)piperazine
CAS No.:87394-66-9
Molecular Formula:C₉H₁₂ClN₃
Molecular Weight:197.667
Hs Code.:
European Community (EC) Number:817-036-5
ChEMBL ID:CHEMBL47740

Synonyms:1-(3-chloropyridin-4-yl)piperazine;87394-66-9;CHEMBL47740;SCHEMBL1904695;BDBM50027012;GS0851;AKOS016937844;AT18163;1-(3-Chloro-pyridin-4-yl)-piperazine;CS-0223994;EN300-117352;Z1262569733

Suppliers and Price of 1-(3-Chloropyridin-4-yl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(3-Chloropyridin-4-yl)piperazine 95%
250mg
$ 348.00

AK Scientific
1-(3-Chloropyridin-4-yl)piperazine
250mg
$ 399.00

AK Scientific
1-(3-Chloropyridin-4-yl)piperazine
5g
$ 2222.00

AccelPharmtech
1-(3-chloro-4-pyridinyl)-Piperazine 97.00%
5G
$ 3230.00

AccelPharmtech
1-(3-chloro-4-pyridinyl)-Piperazine 97.00%
1G
$ 1890.00

Total 5 raw suppliers

Chemical Property of 1-(3-Chloropyridin-4-yl)piperazine

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:197.0719751
Heavy Atom Count:13
Complexity:159

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Chloropyridin-4-yl)piperazine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCN1)C2=C(C=NC=C2)Cl

Technology Process of 1-(3-Chloropyridin-4-yl)piperazine

There total 4 articles about 1-(3-Chloropyridin-4-yl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 683240-48-4
tert-butyl 4-(3-chloropyridin-4-yl)piperazine-1-carboxylate

: 87394-66-9
1-(3-chloropyridin-4-yl)piperazine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jm060065y

Reference yield: 41.0%

: 87394-66-9
1-(3-chloropyridin-4-yl)piperazine

Guidance literature:

Reference yield:

: 55934-00-4
3,4-dichloropyridine

: 87394-66-9
1-(3-chloropyridin-4-yl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / K₂CO₃; Cu / dimethylformamide / 130 °C

2: 99 percent / TFA / CH₂Cl₂ / 2 h / 20 °C

With copper; potassium carbonate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm060065y