2-(Cyclopentanesulfonyl)aniline

Base Information

Chemical Name:2-(Cyclopentanesulfonyl)aniline
CAS No.:76697-51-3
Molecular Formula:C₁₁H₁₅NO₂S
Molecular Weight:225.312
Hs Code.:
European Community (EC) Number:883-427-2
DSSTox Substance ID:DTXSID601297872

Synonyms:2-(cyclopentanesulfonyl)aniline;76697-51-3;2-(cyclopentylsulfonyl)aniline;2-cyclopentylsulfonylaniline;SCHEMBL2521493;2-Cyclopentanesulfonylphenylamine;NDFGZXFQVSEJDM-UHFFFAOYSA-N;2-(Cyclopentylsulfonyl)benzenamine;DTXSID601297872;AKOS009256056;CS-0247256;EN300-36174;Z362768112

Suppliers and Price of 2-(Cyclopentanesulfonyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Cyclopentylsulfonylaniline
500mg
$ 75.00

American Custom Chemicals Corporation
2-(CYCLOPENTYLSULFONYL)ANILINE 95.00%
5G
$ 1759.28

American Custom Chemicals Corporation
2-(CYCLOPENTYLSULFONYL)ANILINE 95.00%
2.5G
$ 1363.65

American Custom Chemicals Corporation
2-(CYCLOPENTYLSULFONYL)ANILINE 95.00%
1G
$ 925.31

AK Scientific
2-(Cyclopentanesulfonyl)aniline
500mg
$ 176.00

aablocks
2-(cyclopentanesulfonyl)aniline 95.0%
1g
$ 115.00

aablocks
2-(cyclopentanesulfonyl)aniline 95.0%
250mg
$ 101.00

Total 5 raw suppliers

Chemical Property of 2-(Cyclopentanesulfonyl)aniline

Chemical Property:

Melting Point:88 - 90°C
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), DMSO (Slightly, Heated)
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:225.08234989
Heavy Atom Count:15
Complexity:301

Purity/Quality:

97% ^*data from raw suppliers

2-Cyclopentylsulfonylaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(C1)S(=O)(=O)C2=CC=CC=C2N
Uses 2-Cyclopentylsulfonylaniline is use in preparation of anaplastic lymphoma kinase inhibitor.

Technology Process of 2-(Cyclopentanesulfonyl)aniline

There total 4 articles about 2-(Cyclopentanesulfonyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.2%

: 76697-44-4
Cyclopentyl-(2-nitrophenyl)-sulfon

: 76697-51-3
2-Aminophenyl-cyclopentyl-sulfon

Guidance literature:: With hydrogenchloride; iron; In ethanol; water; 1.) 75-80 deg C, 40 min 2.) reflux, 2 h;
DOI:10.1002/hlca.19800630610

Reference yield:

: 137-43-9
Cyclopentyl bromide

: 76697-51-3
2-Aminophenyl-cyclopentyl-sulfon

Guidance literature:: Multi-step reaction with 3 steps

1: 92.7 percent / 1.) NaOH / ethanol / 1.) 15 min 2.) reflux, 14 h

2: 88.2 percent / H₂O₂ / acetic acid / 1.) below 80 deg C, 80 min 2.) reflux, 2 h

3: 79.2 percent / Fe powder, HCl / ethanol; H₂O / 1.) 75-80 deg C, 40 min 2.) reflux, 2 h

With hydrogenchloride; sodium hydroxide; dihydrogen peroxide; iron; In ethanol; water; acetic acid;
DOI:10.1002/hlca.19800630610

Reference yield:

: 4875-10-9
o-nitrothiophenol

: 76697-51-3
2-Aminophenyl-cyclopentyl-sulfon

Guidance literature:: Multi-step reaction with 3 steps

1: 92.7 percent / 1.) NaOH / ethanol / 1.) 15 min 2.) reflux, 14 h

2: 88.2 percent / H₂O₂ / acetic acid / 1.) below 80 deg C, 80 min 2.) reflux, 2 h

3: 79.2 percent / Fe powder, HCl / ethanol; H₂O / 1.) 75-80 deg C, 40 min 2.) reflux, 2 h

With hydrogenchloride; sodium hydroxide; dihydrogen peroxide; iron; In ethanol; water; acetic acid;
DOI:10.1002/hlca.19800630610