4-(Trifluoromethyl)pyridine-3-sulfonyl chloride

Base Information

Chemical Name:4-(Trifluoromethyl)pyridine-3-sulfonyl chloride
CAS No.:533932-27-3
Molecular Formula:C₆H₃ClF₃NO₂S
Molecular Weight:245.61
Hs Code.:
European Community (EC) Number:858-095-7

Synonyms:4-(TRIFLUOROMETHYL)PYRIDINE-3-SULFONYL CHLORIDE;533932-27-3;SCHEMBL4998731;GS2972;AKOS006336033;AB67946;AT11609;4-Trifluoromethyl-pyridine-3-sulfonyl chloride;EN300-170028;4-(TRIFLUOROMETHYL)PYRIDINE-3-SULFONYLCHLORIDE

Suppliers and Price of 4-(Trifluoromethyl)pyridine-3-sulfonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
4-(TRIFLUOROMETHYL)PYRIDINE-3-SULFONYLCHLORIDE 95
1g
$ 1416.00

AK Scientific
4-(Trifluoromethyl)pyridine-3-sulfonylchloride
1g
$ 1063.00

AK Scientific
4-(Trifluoromethyl)pyridine-3-sulfonylchloride
500mg
$ 851.00

AK Scientific
4-(Trifluoromethyl)pyridine-3-sulfonylchloride
100mg
$ 433.00

Total 2 raw suppliers

Chemical Property of 4-(Trifluoromethyl)pyridine-3-sulfonyl chloride

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:244.9525117
Heavy Atom Count:14
Complexity:297

Purity/Quality:

98%min ^*data from raw suppliers

4-(TRIFLUOROMETHYL)PYRIDINE-3-SULFONYLCHLORIDE 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CN=CC(=C1C(F)(F)F)S(=O)(=O)Cl

Technology Process of 4-(Trifluoromethyl)pyridine-3-sulfonyl chloride

There total 4 articles about 4-(Trifluoromethyl)pyridine-3-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3-benzylsulfanyl-4-trifluoromethylpyridine

: 533932-27-3
4-(trifluoromethyl)pyridine-3-sulfonyl chloride

Guidance literature:: With N-chloro-succinimide; acetic acid; In water; at 0 - 20 ℃;
DOI:10.1002/anie.201906075

Reference yield:

: 3-benzylsulfanyl-4-trifluoromethylpyridine

: 3-(benzylsulfanyl-phenyl-methyl-sulfanyl)-4-trifluoromethylpyridine

: 533932-27-3
4-(trifluoromethyl)pyridine-3-sulfonyl chloride

Guidance literature:: With hydrogenchloride; sodium hypochlorite; In dichloromethane; water; at 0 - 5 ℃; for 1.25h;

Reference yield:

: 3796-24-5
4-trifluoromethylpyridine

: 533932-27-3
4-(trifluoromethyl)pyridine-3-sulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 2 h / -70 - -60 °C

1.2: 2 h / -60 - 20 °C

2.1: hydrogenchloride; sodium hypochlorite / dichloromethane; water / 1.25 h / 0 - 5 °C

With hydrogenchloride; sodium hypochlorite; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; water;