intermediate 7

Base Information

Chemical Name:intermediate 7
CAS No.:625127-11-9
Molecular Formula:C₁₀H₉F₄N
Molecular Weight:219.182
Hs Code.:

Synonyms:

Suppliers and Price of intermediate 7

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Fluoro-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinolinehydrochloride 97%
1g
$ 1148.00

Chemenu
5-Fluoro-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinolinehydrochloride 97%
1g
$ 1082.00

Total 1 raw suppliers

Chemical Property of intermediate 7

Chemical Property:

Boiling Point:224.7±40.0 °C(Predicted)
Density:1.289±0.06 g/cm3(Predicted)

Purity/Quality:: 5-Fluoro-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinolinehydrochloride 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of intermediate 7

There total 3 articles about intermediate 7 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 625127-13-1
2,2,2-trifluoro-1-(5-fluoro-7-trifluoromethyl-3,4-dihydro-1H-isoquinolln-2-yI)-ethanone

: 625127-11-9
intermediate 7

Guidance literature:: With ethanol; water; potassium carbonate; for 1h; Heating / reflux;

Reference yield:

: 625127-12-0
2,2, 2-trifluoro-N-[2-(2-fluoro-4-trifluoromethyl-phenyl)-ethyl]-acetamide

: 625127-11-9
intermediate 7

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid; acetic acid / 16 h / 0 - 20 °C

2: potassium carbonate; water / ethanol / 15 h / Reflux

With sulfuric acid; water; potassium carbonate; acetic acid; In ethanol;

Reference yield:

: 885068-05-3
2-(2-fluoro-4-trifluoromethyl-phenyl)-ethylamine hydrochloride

: 625127-11-9
intermediate 7

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / 0 - 20 °C

2: sulfuric acid; acetic acid / 16 h / 0 - 20 °C

3: potassium carbonate; water / ethanol / 15 h / Reflux

With sulfuric acid; water; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; In ethanol; dichloromethane;