2-(naphthalen-2’-yl)benzaldehyde

Base Information

• Chemical Name: 2-(naphthalen-2’-yl)benzaldehyde
• CAS No.: 223575-47-1
• Molecular Formula: C₁₇H₁₂O
• Molecular Weight: 232.282
• Mol file: 223575-47-1.mol

Synonyms:

Chemical Property of 2-(naphthalen-2’-yl)benzaldehyde

Chemical Property:

Purity/Quality:

95%-98% ^*data from raw suppliers

2-(Naphthalen-2-yl)benzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(naphthalen-2’-yl)benzaldehyde

There total 36 articles about 2-(naphthalen-2’-yl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

naphthalene-2-boronic acid (32316-92-0) + ortho-bromobenzaldehyde (6630-33-7) → 2-(naphthalen-2’-yl)benzaldehyde (223575-47-1)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; triphenylphosphine; In ethanol; water; at 95 ℃; Inert atmosphere;

DOI:10.1021/jacs.9b10645

Reference yield: 93.0%

2-iodobenzaldehyde (26260-02-6) + tris(β-naphthyl)bismuth → 2-(naphthalen-2’-yl)benzaldehyde (223575-47-1)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; caesium carbonate; In N,N-dimethyl acetamide; at 90 ℃; for 5h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c4ra13348j

Reference yield: 92.0%

2-[(tert-butylimino)methyl]-N,N-dimethylaniline + 2-naphthalenylmagnesium bromide (21473-01-8) → 2-(naphthalen-2’-yl)benzaldehyde (223575-47-1)

Guidance literature:

2-[(tert-butylimino)methyl]-N,N-dimethylaniline; 2-naphthalenylmagnesium bromide; With chromium dichloride; In tetrahydrofuran; at 20 ℃; for 16h;

With hydrogenchloride; water; at 20 ℃; for 0.5h; Reagent/catalyst; Mechanism;

DOI:10.1021/jacs.0c05730

upstream raw materials:

naphthalene-2-boronic acid

ortho-bromobenzaldehyde

1-Iodonaphthalene

o-bromobenzyl alcohol

Downstream raw materials:

benzo[c]phenanthridine