benzo[b]thiophene-7-carboxamide

Base Information

• Chemical Name: benzo[b]thiophene-7-carboxamide
• CAS No.: 959756-04-8
• Molecular Formula: C₉H₇NOS
• Molecular Weight: 177.227

Synonyms:

Chemical Property of benzo[b]thiophene-7-carboxamide

Chemical Property:

• Boiling Point: 411.5±18.0 °C(Predicted)
• Density: 1.345±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

BENZO[B]THIOPHENE-7-CARBOXAMIDE >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzo[b]thiophene-7-carboxamide

There total 3 articles about benzo[b]thiophene-7-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzothiophen-7-carboxic acid (10134-98-2) → benzo[b]thiophene-7-carboxamide (959756-04-8)

Guidance literature:

benzothiophen-7-carboxic acid; With oxalyl dichloride; In tetrahydrofuran; for 3h; Reflux; Cooling with ice;

With ammonium hydroxide; In tetrahydrofuran; at 20 ℃; for 1h;

Reference yield:

benzo[b]thiophene-7-carbonyl chloride (120081-47-2) → benzo[b]thiophene-7-carboxamide (959756-04-8)

Guidance literature:

benzo[b]thiophene-7-carbonyl chloride; With ammonia; In dichloromethane; water;

With sodium hydrogencarbonate; In dichloromethane; water;

Reference yield:

benzo[b]thiophene-7-carboxylic acid ethyl ester (959632-57-6) → benzo[b]thiophene-7-carboxamide (959756-04-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydroxide; water / methanol / 0.5 h / 20 °C

1.2: pH 1

2.1: thionyl chloride / N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C

3.1: ammonia / dichloromethane; water

With sodium hydroxide; thionyl chloride; ammonia; water; N,N-dimethyl-formamide; In methanol; dichloromethane; water;

upstream raw materials:

benzo[b]thiophene-7-carbonyl chloride

benzothiophen-7-carboxic acid

benzo[b]thiophene-7-carboxylic acid ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 959756-04-8 benzo[b]thiophene-7-carboxamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send