trans-2-(allylamino)cyclohexanol

Base Information

• Chemical Name: trans-2-(allylamino)cyclohexanol
• CAS No.: 152857-38-0
• Molecular Formula: C₉H₁₇NO
• Molecular Weight: 155.24
• Mol file: 152857-38-0.mol

Synonyms:

Chemical Property of trans-2-(allylamino)cyclohexanol

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

(1R,2R)-2-(ALLYLAMINO)CYCLOHEXANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of trans-2-(allylamino)cyclohexanol

There total 4 articles about trans-2-(allylamino)cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

cyclohexane-1,2-epoxide (286-20-4) + 1-amino-2-propene (107-11-9,30551-89-4) → trans-2-(allylamino)cyclohexan-1-ol (152857-38-0)

Guidance literature:

for 120h; Heating;

Reference yield: 43.0%

cyclohexane-1,2-epoxide (286-20-4) + 1-amino-2-propene (107-11-9,30551-89-4) → 2-(allylamino)cyclohexan-1-ol (77529-74-9,152857-38-0)

Guidance literature:

cyclohexane-1,2-epoxide; 1-amino-2-propene; In N,N-dimethyl-formamide; at 60 ℃; for 12h; Sealed tube;

With water; In N,N-dimethyl-formamide; at 60 ℃; for 12h; chemoselective reaction; Sealed tube;

DOI:10.1055/s-0036-1588356

Reference yield:

cyclohexene oxide (286-20-4) + 1-amino-2-propene (107-11-9,30551-89-4) → trans-2-(allylamino)cyclohexanol (152857-38-0) + C9H17NO

Guidance literature:

With soyafibe S-DN; In water; toluene; at 40 ℃; for 144h;

DOI:10.3390/molecules25143197

upstream raw materials:

cyclohexane-1,2-epoxide

1-amino-2-propene

magnesium bromide diethyl etherate

cyclohexene oxide

Refernces

• 1、 Asano, Tatsuhiro,Kurata, Hiroyuki,Takeuchi, Yuki,Tsuzaki, Kazuya,Wada, Koichi. "Asymmetric amination of meso-epoxide with vegetable powder as a low-toxicity catalyst". . . Retrieved 2020/08/11.
• 2、 Li, Yang,Tan, Yi,Herdtweck, Eberhardt,Cokoja, Mirza,Kühn, Fritz E.. "Synthesis of nitrile coordinated Lewis acids Al(OC(CF3) 2R)3 and their application in catalytic epoxide ring-opening reactions". experimental part. p. 171 - 176. Retrieved 2010/11/04.