iMAC2

Base Information

Chemical Name:iMAC2
CAS No.:335166-36-4
Molecular Formula:C₁₉H₂₀Br₂FN₃
Molecular Weight:469.194
Hs Code.:
Mol file:335166-36-4.mol

Synonyms:

Suppliers and Price of iMAC2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3,6-DIBROMO-9-[2-FLUORO-3-(1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE 95.00%
50MG
$ 1407.95

American Custom Chemicals Corporation
3,6-DIBROMO-9-[2-FLUORO-3-(1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE 95.00%
10MG
$ 768.08

Total 8 raw suppliers

Chemical Property of iMAC2

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

3,6-DIBROMO-9-[2-FLUORO-3-(1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of iMAC2

There total 7 articles about iMAC2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 335166-01-3
(+/-)-4-[3-(3,6-dibromocarbazol-9-yl)-2-fluoropropyl]piperazine-1-carboxylic acid tert-butyl ester

: 335166-36-4
(+/-)-3,6-Dibromo-9-(2-fluoro-3-piperazin-1-yl-propyl)-carbazole

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1021/jm034107j

Reference yield: 80.0%

: 335165-67-8
(+/-)-4-[3-(3,6-dibromocarbazol-9-yl)-2-hydroxypropyl]piperazine-1-carboxylic acid tert-butyl ester

: 335166-36-4
(+/-)-3,6-Dibromo-9-(2-fluoro-3-piperazin-1-yl-propyl)-carbazole

: 335166-01-3
(+/-)-4-[3-(3,6-dibromocarbazol-9-yl)-2-fluoropropyl]piperazine-1-carboxylic acid tert-butyl ester

Guidance literature:: With trans-4,4'-diaminostilbene-2,2'-disulfonic acid; sodium hydrogencarbonate; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

Reference yield:

: 6825-20-3
3,6-dibromo-9H-carbazole

: 335166-36-4
(+/-)-3,6-Dibromo-9-(2-fluoro-3-piperazin-1-yl-propyl)-carbazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / tetrahydrofuran / 0.5 h / 20 °C

1.2: 72 percent / tetrahydrofuran / 16 h / 20 °C

2.1: 37 percent / (diethylamino)sulfur trifluoride / CH₂Cl₂ / 4 h / 0 °C

3.1: 93 percent / TFA / CH₂Cl₂ / 1 h / 20 °C

With diethylamino-sulfur trifluoride; sodium hydride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm034107j