4-Fluoro-1,4'-bipiperidine dihydrochloride

Base Information

Chemical Name:4-Fluoro-1,4'-bipiperidine dihydrochloride
CAS No.:864291-95-2
Molecular Formula:C₁₀H₁₉FN₂
Molecular Weight:186.273
Hs Code.:
DSSTox Substance ID:DTXSID20697451

Synonyms:4-FLUORO-1,4'-BIPIPERIDINE DIHYDROCHLORIDE;DTXSID20697451;4-Fluoro-1,4'-bipiperidine hydrochloride;F80860;4-Fluoro-1,4'-bipiperidine--hydrogen chloride (1/2)

Suppliers and Price of 4-Fluoro-1,4'-bipiperidine dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
4-Fluoro-1,4'-bipiperidine2HCl 97%
0.25g
$ 284.20

Total 1 raw suppliers

Chemical Property of 4-Fluoro-1,4'-bipiperidine dihydrochloride

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:258.1065822
Heavy Atom Count:15
Complexity:149

Purity/Quality:

98% ^*data from raw suppliers

4-Fluoro-1,4'-bipiperidine2HCl 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CNCCC1N2CCC(CC2)F.Cl.Cl

Technology Process of 4-Fluoro-1,4'-bipiperidine dihydrochloride

There total 6 articles about 4-Fluoro-1,4'-bipiperidine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1335116-37-4
1,1-dimethylethyl 4-fluoro-1,4'-bipiperidine-1'-carboxylate

: 864291-95-2
4-fluoro-1,4'-bipiperidine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 18h;

Reference yield:

: 864293-20-9
benzyl 4-fluoro-1,4'-bipiperidine-1'-carboxylate

: 864291-95-2
4-fluoro-1,4'-bipiperidine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 6h; under 760.051 Torr;
DOI:10.1016/j.bmc.2008.05.036

Reference yield:

: 367500-88-7
4-hydroxy-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester

: 864291-95-2
4-fluoro-1,4'-bipiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: (bis-(2-methoxyethyl)amino)sulfur trufluoride / 2.5 h / -78 - 20 °C

2: hydrogenchloride / 1,4-dioxane / 18 h / 20 °C

With hydrogenchloride; (bis-(2-methoxyethyl)amino)sulfur trufluoride; In 1,4-dioxane;