7-Hydroxy-10,10-dimethyl-7-phenylpyrido[1,2-a]indole-6,8(7H,10H)-dione

Base Information

Chemical Name:7-Hydroxy-10,10-dimethyl-7-phenylpyrido[1,2-a]indole-6,8(7H,10H)-dione
CAS No.:227754-53-2
Molecular Formula:C₂₀H₁₇NO₃
Molecular Weight:319.36
Hs Code.:
DSSTox Substance ID:DTXSID90945456

Synonyms:DTXSID90945456;7-Hydroxy-10,10-dimethyl-7-phenylpyrido[1,2-a]indole-6,8(7H,10H)-dione;227754-53-2

Suppliers and Price of 7-Hydroxy-10,10-dimethyl-7-phenylpyrido[1,2-a]indole-6,8(7H,10H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-Hydroxy-10,10-dimethyl-7-phenylpyrido[1,2-a]indole-6,8(7H,10H)-dione

Chemical Property:

Vapor Pressure:3.67E-11mmHg at 25°C
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:319.12084340
Heavy Atom Count:24
Complexity:602

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(C2=CC=CC=C2N3C1=CC(=O)C(C3=O)(C4=CC=CC=C4)O)C
Isomeric SMILES:CC1(C2=CC=CC=C2N3C1=CC(=O)[C@](C3=O)(C4=CC=CC=C4)O)C

Technology Process of 7-Hydroxy-10,10-dimethyl-7-phenylpyrido[1,2-a]indole-6,8(7H,10H)-dione

There total 5 articles about 7-Hydroxy-10,10-dimethyl-7-phenylpyrido[1,2-a]indole-6,8(7H,10H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 274691-31-5
8-hydroxy-10,10-dimethyl-7-phenyl-10H-pyrido[1,2-a]indol-6-one

: 227754-53-2
7-hydroxy-10,10-dimethyl-7-phenyl-10H-pyrido[1,2-a]indole-6,8(7H)-dione

Guidance literature:: With nitric acid; In acetic acid; for 0.25h; Heating;
DOI:10.1002/jhet.5570390224

Reference yield: 97.0%

: 465540-86-7
10,10-dimethyl-7-nitro-7-phenyl-10H-pyrido[1,2-a]indole-6,8(7H)-dione

: 227754-53-2
7-hydroxy-10,10-dimethyl-7-phenyl-10H-pyrido[1,2-a]indole-6,8(7H)-dione

Guidance literature:: With acetic acid; for 0.166667h; Heating;
DOI:10.1002/jhet.5570390224

Reference yield:

: 563-80-4
3-methyl-butan-2-one

: 227754-53-2
7-hydroxy-10,10-dimethyl-7-phenyl-10H-pyrido[1,2-a]indole-6,8(7H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 56 percent / glacial acetic acid / 2 h / Heating

2: 81 percent / diphenyl ether / 1 h / 260 °C

3: 97 percent / concd. nitric acid / acetic acid / 0.25 h / Heating

With nitric acid; acetic acid; In diphenylether; acetic acid;
DOI:10.1002/jhet.5570390224