prasterone trifluoroacetate triflate

Base Information

• Chemical Name: prasterone trifluoroacetate triflate
• CAS No.: 1802323-89-2
• Molecular Formula: C₂₂H₂₆F₆O₅S
• Molecular Weight: 516.502
• Mol file: 1802323-89-2.mol

Synonyms:

Chemical Property of prasterone trifluoroacetate triflate

Chemical Property:

• Boiling Point: 486.6±45.0 °C(Predicted)
• Density: 1.42±0.1 g/cm3(Predicted)

Purity/Quality:

99.9% ^*data from raw suppliers

(3S,10R,13S)-10,13-dimethyl-17-(trifluoromethylsulfonyloxy)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1Hcyclopenta[a]phenanthren-3-yl2,2,2-trifluoroacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (3S,10R,13S)-10,13-dimethyl-17-(trifluoromethylsulfonyloxy)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1Hcyclopenta[a]phenanthren-3-yl 2,2,2-trifluoroacetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. (Abiraterone Impurity 8).

Technology Process of prasterone trifluoroacetate triflate

There total 1 articles about prasterone trifluoroacetate triflate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trifluoromethylsulfonic anhydride (358-23-6) + 3β-trifluoroacetoxyandrost-5-en-17-one → prasterone trifluoroacetate triflate (1802323-89-2)

Guidance literature:

With sodium carbonate; In dichloromethane; at -10 ℃; for 12h; Reagent/catalyst; Temperature;

upstream raw materials:

trifluoromethylsulfonic anhydride