7-methyl-1H-indol-5-ol

Base Information

Chemical Name:7-methyl-1H-indol-5-ol
CAS No.:53233-87-7
Molecular Formula:C₉H₉NO
Molecular Weight:147.177
Hs Code.:
European Community (EC) Number:842-895-8

Synonyms:7-methyl-1H-indol-5-ol;53233-87-7;SCHEMBL1997793;5-Hydroxy-7-methyl-1H-indole;IGYHZJNICRWVJU-UHFFFAOYSA-N;AKOS006380814;AT38545;SB15110;DB-156676;CS-0139955;EN300-6464376;Z1203832444

Suppliers and Price of 7-methyl-1H-indol-5-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
7-methyl-1H-indol-5-ol 95+%
1g
$ 388.00

Total 11 raw suppliers

Chemical Property of 7-methyl-1H-indol-5-ol

Chemical Property:

Boiling Point:342.7±22.0 °C(Predicted)
Density:1.262±0.06 g/cm3(Predicted)
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:147.068413911
Heavy Atom Count:11
Complexity:149

Purity/Quality:

97% ^*data from raw suppliers

7-methyl-1H-indol-5-ol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC2=C1NC=C2)O

Technology Process of 7-methyl-1H-indol-5-ol

There total 1 articles about 7-methyl-1H-indol-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 65673-86-1
2,3-dihydro-7-methylindole

: 53233-87-7
7-methyl-1H-indol-5-ol

Guidance literature:: With potassium nitrosodisulfonate; sodium phosphate; In water; acetone; at 20 ℃; for 0.5h; pH=7;

Reference yield:

: 53233-87-7
7-methyl-1H-indol-5-ol

: 2-(5-methoxy-7-methyl-1-tosyl-1H-indole-4-carbonyl)-3-((2-(trimethylsilyl)ethoxy)methyl)-3H-imidazo[4,5-b]pyridine-6-carbonitrile

Guidance literature:: Multi-step reaction with 10 steps

1.1: cyanomethylenetributyl-phosphorane / toluene / 1 h / 100 °C

2.1: 0.1 h / 230 °C

3.1: cyanomethylenetributyl-phosphorane / toluene / 1 h / 110 °C

4.1: dmap / acetonitrile / 20 °C

5.1: palladium diacetate / 4 h / 20 °C

6.1: 2,6-dimethylpyridine; osmium(VIII) oxide; sodium periodate / water; 1,4-dioxane / 1 h / 0 - 20 °C

7.1: lithium diisopropyl amide / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere

7.2: 0.5 h / -78 °C

8.1: manganese(IV) oxide / dichloromethane / 16 h / 20 °C

9.1: potassium carbonate; isopropyl alcohol / 2 h / 65 °C

10.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C

10.2: 1 h

With 2,6-dimethylpyridine; dmap; manganese(IV) oxide; sodium periodate; osmium(VIII) oxide; palladium diacetate; sodium hydride; potassium carbonate; isopropyl alcohol; cyanomethylenetributyl-phosphorane; lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile;

Reference yield:

: 53233-87-7
7-methyl-1H-indol-5-ol

: 2-(2-(5-methoxy-7-methyl-1-tosyl-1H-indol-4-yl)propan-2-yl)-3H-imidazo [4,5-b]pyridine-6-carbonitrile

Guidance literature:: Multi-step reaction with 11 steps

1.1: cyanomethylenetributyl-phosphorane / toluene / 1 h / 100 °C

2.1: 0.1 h / 230 °C

3.1: cyanomethylenetributyl-phosphorane / toluene / 1 h / 110 °C

4.1: dmap / acetonitrile / 20 °C

5.1: palladium diacetate / 4 h / 20 °C

6.1: 2,6-dimethylpyridine; osmium(VIII) oxide; sodium periodate / water; 1,4-dioxane / 1 h / 0 - 20 °C

7.1: lithium diisopropyl amide / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere

7.2: 0.5 h / -78 °C

8.1: manganese(IV) oxide / dichloromethane / 16 h / 20 °C

9.1: potassium carbonate; isopropyl alcohol / 2 h / 65 °C

10.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C

10.2: 1 h

11.1: titanium tetrachloride / dichloromethane / 0.25 h / 0 - 20 °C

11.2: 16 h / -40 - 20 °C

With 2,6-dimethylpyridine; dmap; manganese(IV) oxide; sodium periodate; osmium(VIII) oxide; palladium diacetate; titanium tetrachloride; sodium hydride; potassium carbonate; isopropyl alcohol; cyanomethylenetributyl-phosphorane; lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile;