(E)-5-(((2,4,6-Trimethoxystyryl)sulfonyl)methyl)-2-methoxyphenol

Base Information

Chemical Name:(E)-5-(((2,4,6-Trimethoxystyryl)sulfonyl)methyl)-2-methoxyphenol
CAS No.:865783-95-5
Molecular Formula:C₁₉H₂₂O₇S
Molecular Weight:394.445
Hs Code.:
UNII:J3I19I491A
ChEMBL ID:CHEMBL253178
Wikidata:Q27281151

Synonyms:(E)-2,4,6-trimethoxystyryl-3- hydroxy-4-methoxybenzyl sulfone;ON 013100;ON013100

Suppliers and Price of (E)-5-(((2,4,6-Trimethoxystyryl)sulfonyl)methyl)-2-methoxyphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
ON-013100 >98%
250 mg
$ 1200.00

DC Chemicals
ON-013100 >98%
1 g
$ 2400.00

DC Chemicals
ON-013100 >98%
100 mg
$ 700.00

ChemScene
ON-013100 98.23%
50mg
$ 620.00

ChemScene
ON-013100 98.23%
10mg
$ 220.00

ChemScene
ON-013100 98.23%
5mg
$ 140.00

ChemScene
ON-013100 98.23%
1mg
$ 90.00

ChemScene
ON-013100 98.23%
100mg
$ 920.00

Biorbyt Ltd
ON-013100
1 g
$ 3580.20

Biorbyt Ltd
ON-013100
250 mg
$ 1802.00

Total 7 raw suppliers

Chemical Property of (E)-5-(((2,4,6-Trimethoxystyryl)sulfonyl)methyl)-2-methoxyphenol

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:394.10862421
Heavy Atom Count:27
Complexity:557

Purity/Quality:

97% ^*data from raw suppliers

ON-013100 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)O
Isomeric SMILES:COC1=C(C=C(C=C1)CS(=O)(=O)/C=C/C2=C(C=C(C=C2OC)OC)OC)O

Technology Process of (E)-5-(((2,4,6-Trimethoxystyryl)sulfonyl)methyl)-2-methoxyphenol

There total 13 articles about (E)-5-(((2,4,6-Trimethoxystyryl)sulfonyl)methyl)-2-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: (E)-2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenyl-4-methylbenzenesulfonate

: 865783-95-5
(E)-2-methoxy-5-((2,4,6-trimethoxystyrylsulfonyl)methyl)phenol

Guidance literature:: With sodium hydroxide; In methanol; at 65 ℃;
DOI:10.1021/jm701077b

Reference yield: 62.5%

: 865783-98-8
3-hydroxy-4-methoxybenzylsulfonylacetic acid

: 830-79-5
2,4,6-trimethoxybenzaldehyde

: 865783-95-5
(E)-2-methoxy-5-((2,4,6-trimethoxystyrylsulfonyl)methyl)phenol

Guidance literature:: With piperidine; benzoic acid; In toluene; for 2 - 3h; Heating / reflux;

Reference yield:

: 621-59-0
isovanillin

: 865783-95-5
(E)-2-methoxy-5-((2,4,6-trimethoxystyrylsulfonyl)methyl)phenol

Guidance literature:: Multi-step reaction with 7 steps

1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.17 h / 0 °C

1.2: 12.5 - 16.5 h

2.1: sodium tetrahydroborate / methanol / 0.5 h / 0 - 20 °C

2.2: 0 °C

3.1: thionyl chloride / benzene / 0.17 h / 0 °C

4.1: sodium hydroxide / methanol / 0.17 h

4.2: 20 °C

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C

6.1: dihydrogen peroxide; acetic acid / water / 20 °C

7.1: piperidine; benzoic acid / toluene / 2 - 3 h / Heating / reflux

With piperidine; sodium hydroxide; sodium tetrahydroborate; thionyl chloride; tetrabutyl ammonium fluoride; dihydrogen peroxide; acetic acid; N-ethyl-N,N-diisopropylamine; benzoic acid; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; toluene; benzene;