5-(4-phenyl-butyl)-thiophene-2-carboxylic acid

Base Information

Chemical Name:5-(4-phenyl-butyl)-thiophene-2-carboxylic acid
CAS No.:859491-10-4
Molecular Formula:C₁₅H₁₆O₂S
Molecular Weight:260.357
Hs Code.:

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Chemical Property of 5-(4-phenyl-butyl)-thiophene-2-carboxylic acid

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Technology Process of 5-(4-phenyl-butyl)-thiophene-2-carboxylic acid

There total 4 articles about 5-(4-phenyl-butyl)-thiophene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 148112-00-9
2-(4-phenylbutyl)thiophene

: 859491-10-4
5-(4-phenyl-butyl)-thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: aluminium chloride; carbon disulfide

2: alkaline aqueous sodium hypobromite solution

With carbon disulfide; aluminium trichloride; alkaline aqueous sodium hypobromite solution;

Reference yield:

: 874525-54-9
1-(2-thienyl)-4-phenylbutan-1-one

: 859491-10-4
5-(4-phenyl-butyl)-thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine hydrate; potassium hydroxide; diethylene glycol

2: aluminium chloride; carbon disulfide

3: alkaline aqueous sodium hypobromite solution

With carbon disulfide; potassium hydroxide; aluminium trichloride; alkaline aqueous sodium hypobromite solution; hydrazine hydrate; diethylene glycol;

Reference yield:

: 18496-54-3
phenylbutyric acid chloride

: 859491-10-4
5-(4-phenyl-butyl)-thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: tin (IV)-chloride; carbon disulfide

2: hydrazine hydrate; potassium hydroxide; diethylene glycol

3: aluminium chloride; carbon disulfide

4: alkaline aqueous sodium hypobromite solution

With carbon disulfide; potassium hydroxide; aluminium trichloride; alkaline aqueous sodium hypobromite solution; tin(IV) chloride; hydrazine hydrate; diethylene glycol;