ensartinib hydrochloride

Base Information

Chemical Name:ensartinib hydrochloride
CAS No.:2137030-98-7
Molecular Formula:C₂₆H₂₇Cl₂FN₆O₃*(x)ClH
Molecular Weight:597.9
Hs Code.:

Synonyms:

Suppliers and Price of ensartinib hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
Ensartinibhydrochloride 99.46%
10mg
$ 330.00

ChemScene
Ensartinibhydrochloride 99.46%
5mg
$ 180.00

ChemScene
Ensartinibhydrochloride 99.46%
2mg
$ 100.00

Total 6 raw suppliers

Chemical Property of ensartinib hydrochloride

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Ensartinibhydrochloride 99.46% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Ensartinib HCl is the salt form of Ensartinib, an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development.

Technology Process of ensartinib hydrochloride

There total 5 articles about ensartinib hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₄₁H₅₁Cl₂FN₆O₉

: 2137030-98-7
{5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-6-aminopyridazin-3-yl}-N-{4-[((3S,5R)-3,5-dimethylpiperazinyl)carbonyl]phenyl}carboxamide hydrochloride

Guidance literature:: C₄₁H₅₁Cl₂FN₆O₉; With trifluoroacetic acid; In dichloromethane; at -5 - 20 ℃; for 2h;

With hydrogenchloride; In water; isopropyl alcohol; at 10 - 20 ℃;