1-Methoxy-3-[(E)-2-phenylethenyl]benzene

Base Information

• Chemical Name: 1-Methoxy-3-[(E)-2-phenylethenyl]benzene
• CAS No.: 14064-41-6
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• Hs Code.: 2909309090
• Mol file: 14064-41-6.mol

Synonyms:(E)-1-methoxy-3-stytylbenzene;(E)-1-(3-methoxyphenyl)-2-phenylethene;(E)-1-methoxy-3-styrylbenzene;Benzene,1-methoxy-3-[(1E)-2-phenylethenyl];(E)-1-(3-methoxystyryl)benzene;(E)-3-methoxystilbene;Benzene, 1-methoxy-3-(2-phenylethenyl)-, (E)-;3-Methoxy-trans-stilbene;1-(3-methoxyphenyl)-2-phenylethene;(E)-1-methoxy-4-styrylbenzene;

Chemical Property of 1-Methoxy-3-[(E)-2-phenylethenyl]benzene

Chemical Property:

• PSA: 9.23000
• LogP: 3.86560

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Methoxy-3-[(E)-2-phenylethenyl]benzene

There total 88 articles about 1-Methoxy-3-[(E)-2-phenylethenyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 1-chloro-3-methoxy-benzene (2845-89-8) → (E)-3-methoxystilbene (14064-41-6,15638-11-6)

Guidance literature:

With tetrakis[μ-1-[(3-methoxyphenyl)methyl]-2-phenyl-3-[2-oxo-2-[(2-phenolato-kO)aminokN]ethyl]-1H-imidazoliumato-kC⁴]tetrapalladium; tetrabutylammomium bromide; sodium acetate; at 140 ℃; for 12h;

DOI:10.1002/adsc.201900805

Reference yield: 98.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 3-methoxyphenyl bromide (2398-37-0) → (E)-3-methoxystilbene (14064-41-6,15638-11-6)

Guidance literature:

3-methoxyphenyl bromide; With per-6-guanidino-β-cyclodextrin; palladium diacetate; In water; N,N-dimethyl-formamide; for 0.5h;

styrene; With potassium carbonate; In water; N,N-dimethyl-formamide; at 80 ℃; for 13h; Reagent/catalyst;

DOI:10.1002/chem.201301863

Reference yield: 97.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 3-methoxy-1-iodobenzene (766-85-8) → (E)-3-methoxystilbene (14064-41-6,15638-11-6)

Guidance literature:

With palladium diacetate; triethylamine; In acetonitrile; at 85 ℃; for 72h; Inert atmosphere;

DOI:10.1016/j.tet.2013.07.086

upstream raw materials:

(Z)-1-(3-methoxyphenyl)-2-phenylethene

3-methoxy-benzaldehyde

benzylmagnesium chloride

trans-cinnamic acid-(3-methoxy-phenyl ester)

Downstream raw materials:

(E)-3-hydroxystilbene

(Z)-1-(3-methoxyphenyl)-2-phenylethene

3-hydroxystilbene

3-hydroxybibenzyl

Refernces

• 1、 Kon,Spickett. "-". . p. 2724. Retrieved 1949.
• 2、 Leigh, Vivienne,Ghattas, Wadih,Mueller-Bunz, Helge,Albrecht, Martin. "Synthesis of pincer-type N-heterocyclic carbene palladium complexes with a hemilabile ligand and their application in cross-coupling catalysis". . p. 33 - 39. Retrieved 2014.
• 3、 Hung, Cheng-Hau,Zheng, Wei-Yuan,Lee, Hon Man. "Palladium Complexes with Phenoxy- And Amidate-Functionalized N-Heterocyclic Carbene Ligands Based on 3-Phenylimidazo[1,5- a]pyridine: Synthesis and Catalytic Application in Mizoroki-Heck Coupling Reactions with Ortho-Substituted Aryl Chlorides". . p. 702 - 713. Retrieved 2021/04/02.
• 4、 Babu, Reshma,Balaraman, Ekambaram,Midya, Siba P.,Subaramanian, Murugan,Yadav, Vinita. "Tandem Acceptorless Dehydrogenative Coupling-Decyanation under Nickel Catalysis". . p. 7552 - 7562. Retrieved 2021/06/28.