Boc-L-α-Methylphenylvalin*Dicyclohexylamin

Base Information

• Chemical Name: Boc-L-α-Methylphenylvalin*Dicyclohexylamin
• CAS No.: 53940-89-9
• Molecular Formula: C₁₂H₂₃N*C₁₅H₂₁NO₄
• Molecular Weight: 460.657
• Mol file: 53940-89-9.mol

Synonyms:

Chemical Property of Boc-L-α-Methylphenylvalin*Dicyclohexylamin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Boc-L-α-Methylphenylvalin*Dicyclohexylamin

There total 2 articles about Boc-L-α-Methylphenylvalin*Dicyclohexylamin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

DL-N-Trifluoracetyl-α-methylphenylalanin (53940-84-4) → Boc-L-α-Methylphenylvalin*Dicyclohexylamin (53940-89-9)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH / (enzymatic transformation)

2: (i) tetramethylguanidine, (ii) /BRN= 605923/

With sodium hydroxide;

DOI:10.1021/jo00895a032

Reference yield:

N-(tert-butyloxycarbonyl) azide (1070-19-5) + (S)-2-amino-2-methyl-3-phenylpropanoic acid (23239-35-2) + N-cyclohexyl-cyclohexanamine (101-83-7) → Boc-L-α-Methylphenylvalin*Dicyclohexylamin (53940-89-9)

Guidance literature:

Multistep reaction; (i) tetramethylguanidine, (ii) /BRN= 605923/;

DOI:10.1021/jo00895a032

upstream raw materials:

N-(tert-butyloxycarbonyl) azide

(S)-2-amino-2-methyl-3-phenylpropanoic acid

N-cyclohexyl-cyclohexanamine

DL-N-Trifluoracetyl-α-methylphenylalanin