(6aR)-6t,12t-bis-(2,6-dimethoxy-benzoylamino)-2,2,8,8-tetramethyl-5,11-dioxo-(6ar,12ac)-octahydro-bisthiazolo[3,2-a;3',2'-e][1,5]diazocine-3c,9c-dicarboxylic acid

Base Information

• Chemical Name: (6aR)-6t,12t-bis-(2,6-dimethoxy-benzoylamino)-2,2,8,8-tetramethyl-5,11-dioxo-(6ar,12ac)-octahydro-bisthiazolo[3,2-a;3',2'-e][1,5]diazocine-3c,9c-dicarboxylic acid
• CAS No.: 106215-27-4
• Molecular Formula: C₃₄H₄₀N₄O₁₂S₂
• Molecular Weight: 760.843
• Mol file: 106215-27-4.mol

Synonyms:

Chemical Property of (6aR)-6t,12t-bis-(2,6-dimethoxy-benzoylamino)-2,2,8,8-tetramethyl-5,11-dioxo-(6ar,12ac)-octahydro-bisthiazolo[3,2-a;3',2'-e][1,5]diazocine-3c,9c-dicarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6aR)-6t,12t-bis-(2,6-dimethoxy-benzoylamino)-2,2,8,8-tetramethyl-5,11-dioxo-(6ar,12ac)-octahydro-bisthiazolo[3,2-a;3',2'-e][1,5]diazocine-3c,9c-dicarboxylic acid

There total 1 articles about (6aR)-6t,12t-bis-(2,6-dimethoxy-benzoylamino)-2,2,8,8-tetramethyl-5,11-dioxo-(6ar,12ac)-octahydro-bisthiazolo[3,2-a;3',2'-e][1,5]diazocine-3c,9c-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methicillin sodium (132-92-3) → (6aR)-6t,12t-bis-(2,6-dimethoxy-benzoylamino)-2,2,8,8-tetramethyl-5,11-dioxo-(6ar,12ac)-octahydro-bisthiazolo[3,2-a;3',2'-e][1,5]diazocine-3c,9c-dicarboxylic acid (106215-27-4)

Guidance literature:

With hydrogen cation; 4-methyl-2-pentanone; for 168h; Ambient temperature;

DOI:10.1021/jo01030a038

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + (6aR)-6t,12t-bis-(2,6-dimethoxy-benzoylamino)-2,2,8,8-tetramethyl-5,11-dioxo-(6ar,12ac)-octahydro-bisthiazolo[3,2-a;3',2'-e][1,5]diazocine-3c,9c-dicarboxylic acid (106215-27-4) → (6aR)-6t,12t-bis-(2,6-dimethoxy-benzoylamino)-2,2,8,8-tetramethyl-5,11-dioxo-(6ar,12ac)-octahydro-bisthiazolo[3,2-a;3',2'-e][1,5]diazocine-3c,9c-dicarboxylic acid dimethyl ester (106095-84-5)

Guidance literature:

In methanol; diethyl ether;

DOI:10.1021/jo01030a038

upstream raw materials:

methicillin sodium

Downstream raw materials:

(6aR)-6t,12t-bis-(2,6-dimethoxy-benzoylamino)-2,2,8,8-tetramethyl-5,11-dioxo-(6ar,12ac)-octahydro-bisthiazolo[3,2-a;3',2'-e][1,5]diazocine-3c,9c-dicarboxylic acid dimethyl ester