gymnothelignan D

Base Information

• Chemical Name: gymnothelignan D
• CAS No.: 1401068-81-2
• Molecular Formula: C₂₄H₃₂O₈
• Molecular Weight: 448.513
• Mol file: 1401068-81-2.mol

Synonyms:

Chemical Property of gymnothelignan D

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of gymnothelignan D

There total 4 articles about gymnothelignan D which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C15H20O5 → gymnothelignan D (1401068-81-2) + C24H32O8

Guidance literature:

Multi-step reaction with 5 steps

1.1: iodine; silver trifluoroacetate / chloroform / 0.17 h / 20 °C / Inert atmosphere

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate / 1,2-dimethoxyethane; water / 15 h / Reflux

3.1: hydrogen; palladium 10% on activated carbon / ethanol / 0.33 h / 20 °C / Inert atmosphere

4.1: 1H-imidazole / dichloromethane; hexane / 20 °C

4.2: 1.5 h / -78 °C / Inert atmosphere

5.1: toluene-4-sulfonic acid / methanol / 16 h / 20 °C

With 1H-imidazole; tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; hydrogen; iodine; silver trifluoroacetate; sodium hydrogencarbonate; toluene-4-sulfonic acid; In methanol; 1,2-dimethoxyethane; ethanol; hexane; dichloromethane; chloroform; water;

DOI:10.1021/acs.joc.8b00164

Reference yield:

C15H19IO5 → gymnothelignan D (1401068-81-2) + C24H32O8

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate / 1,2-dimethoxyethane; water / 15 h / Reflux

2.1: hydrogen; palladium 10% on activated carbon / ethanol / 0.33 h / 20 °C / Inert atmosphere

3.1: 1H-imidazole / dichloromethane; hexane / 20 °C

3.2: 1.5 h / -78 °C / Inert atmosphere

4.1: toluene-4-sulfonic acid / methanol / 16 h / 20 °C

With 1H-imidazole; tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; toluene-4-sulfonic acid; In methanol; 1,2-dimethoxyethane; ethanol; hexane; dichloromethane; water;

DOI:10.1021/acs.joc.8b00164

Reference yield:

C30H34O8 → gymnothelignan D (1401068-81-2) + C24H32O8

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogen; palladium 10% on activated carbon / ethanol / 0.33 h / 20 °C / Inert atmosphere

2.1: 1H-imidazole / dichloromethane; hexane / 20 °C

2.2: 1.5 h / -78 °C / Inert atmosphere

3.1: toluene-4-sulfonic acid / methanol / 16 h / 20 °C

With 1H-imidazole; palladium 10% on activated carbon; hydrogen; toluene-4-sulfonic acid; In methanol; ethanol; hexane; dichloromethane;

DOI:10.1021/acs.joc.8b00164