(2R)-2-(N-hydroxyamino)-3-phenylpropanoic acid

Base Information

Chemical Name:(2R)-2-(N-hydroxyamino)-3-phenylpropanoic acid
CAS No.:35016-65-0
Molecular Formula:C₉H₁₁NO₃
Molecular Weight:181.191
Hs Code.:
DSSTox Substance ID:DTXSID201312440
Nikkaji Number:J2.485.147H

Synonyms:35016-65-0;Hydroxy-D-phenylalanine;N-Hydroxy-D-phenylalanine;SCHEMBL9508136;DTXSID201312440;(2R)-2-(N-hydroxyamino)-3-phenylpropanoic acid;EN300-7539589

Suppliers and Price of (2R)-2-(N-hydroxyamino)-3-phenylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R)-2-(N-hydroxyamino)-3-phenylpropanoic acid

Chemical Property:

XLogP3:-2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:181.07389321
Heavy Atom Count:13
Complexity:166

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)O)NO
Isomeric SMILES:C1=CC=C(C=C1)C[C@H](C(=O)O)NO

Technology Process of (2R)-2-(N-hydroxyamino)-3-phenylpropanoic acid

There total 3 articles about (2R)-2-(N-hydroxyamino)-3-phenylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 129505-09-5,147383-38-8
(2R,2'R)-N-<2'-(hydroxyamino)-3'-phenylpropanoyl>bornane-10,2-sultam

: 35016-65-0
(2R)-(N-hydroxy)phenylalanine

Guidance literature:: With lithium hydroxide; ion exchange; Yield given. Multistep reaction; 1.) THF;
DOI:10.1016/S0040-4039(00)94411-3

Reference yield:

: 127392-81-8
1-((3aS,6R,7aR)-8,8-dimethyl-2,2-dioxidohexahydro-1H-3a,6-methanobenzo[c]isothiazol-1-yl)-3-phenylpropan-1-one

: 35016-65-0
(2R)-(N-hydroxy)phenylalanine

Guidance literature:: Multi-step reaction with 2 steps

2: 1) 1M aq. LiOH, 2) Dowex 50W-8 (H⁺-form) / 1) THF, 0 deg C, 15 min., 2) H₂O

With lithium hydroxide; Dowex 50W-8 (H⁺-form);
DOI:10.1002/hlca.19920750622

Reference yield:

: 645-45-4
hydrocinnamic acid chloride

: 35016-65-0
(2R)-(N-hydroxy)phenylalanine

Guidance literature:: Multi-step reaction with 3 steps

1: 1) NaH

3: 1) 1M aq. LiOH, 2) Dowex 50W-8 (H⁺-form) / 1) THF, 0 deg C, 15 min., 2) H₂O

With lithium hydroxide; Dowex 50W-8 (H⁺-form); sodium hydride;
DOI:10.1002/hlca.19920750622