(6R,7R)-1-aza-3-methyl-7-(m-carboxyphenylacetyl)-8-oxo-5-thiabicyclo<4.2.0>oct-2-ene carboxylic acid

Base Information

• Chemical Name: (6R,7R)-1-aza-3-methyl-7-(m-carboxyphenylacetyl)-8-oxo-5-thiabicyclo<4.2.0>oct-2-ene carboxylic acid
• CAS No.: 109796-28-3
• Molecular Formula: C₁₇H₁₆N₂O₆S
• Molecular Weight: 376.39
• Mol file: 109796-28-3.mol

Synonyms:

Chemical Property of (6R,7R)-1-aza-3-methyl-7-(m-carboxyphenylacetyl)-8-oxo-5-thiabicyclo<4.2.0>oct-2-ene carboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6R,7R)-1-aza-3-methyl-7-(m-carboxyphenylacetyl)-8-oxo-5-thiabicyclo<4.2.0>oct-2-ene carboxylic acid

There total 1 articles about (6R,7R)-1-aza-3-methyl-7-(m-carboxyphenylacetyl)-8-oxo-5-thiabicyclo<4.2.0>oct-2-ene carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

(2S,5R,6R)-6-(m-carboxyphenylacetyl)-3,3'-dimethyl-7-oxo-1-aza-4-thiabicyclo<3.2.0>heptane-2-carboxylic acid (109796-25-0) → (6R,7R)-1-aza-3-methyl-7-(m-carboxyphenylacetyl)-8-oxo-5-thiabicyclo<4.2.0>oct-2-ene carboxylic acid (109796-28-3)

Guidance literature:

With ring expansion enzyme from Cephalosporium CO₇₂₈; oxygen; α-ketoglutarate; iron(II) sulfate; ascorbic acid; diothiothreitol; at 30 ℃; pH=7.5;

DOI:10.1039/c39870000374

upstream raw materials:

(2S,5R,6R)-6-(m-carboxyphenylacetyl)-3,3'-dimethyl-7-oxo-1-aza-4-thiabicyclo<3.2.0>heptane-2-carboxylic acid