2-(phenoxymethyl)piperidine

Base Information

Chemical Name:2-(phenoxymethyl)piperidine
CAS No.:220510-70-3
Molecular Formula:C₁₂H₁₇NO
Molecular Weight:191.273
Hs Code.:
Mol file:220510-70-3.mol

Synonyms:

Suppliers and Price of 2-(phenoxymethyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(PHENOXYMETHYL)PIPERIDINE 95.00%
5MG
$ 498.27

Acrotein
2-(Phenoxymethyl)-piperidineHCl 97%
1g
$ 440.00

Acrotein
2-(Phenoxymethyl)-piperidineHCl 97%
0.5g
$ 293.33

Total 5 raw suppliers

Chemical Property of 2-(phenoxymethyl)piperidine

Chemical Property:

Purity/Quality:

95%-98% ^*data from raw suppliers

2-(PHENOXYMETHYL)PIPERIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(phenoxymethyl)piperidine

There total 3 articles about 2-(phenoxymethyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 137650-02-3,85387-43-5
(1-benzylpiperidin-2-yl)methanol

: 220510-70-3
2-(phenoxymethyl)piperidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: dmap; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

2.2: 16 h / Inert atmosphere; Reflux

3.1: palladium 10% on activated carbon; hydrogen / methanol; dichloromethane / 16 h / 20 °C

With dmap; palladium 10% on activated carbon; hydrogen; sodium hydride; triethylamine; In tetrahydrofuran; methanol; dichloromethane; mineral oil;
DOI:10.1021/acs.jmedchem.6b01482

Reference yield:

: C₂₀H₂₅NO₃S

: 220510-70-3
2-(phenoxymethyl)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

1.2: 16 h / Inert atmosphere; Reflux

2.1: palladium 10% on activated carbon; hydrogen / methanol; dichloromethane / 16 h / 20 °C

With palladium 10% on activated carbon; hydrogen; sodium hydride; In tetrahydrofuran; methanol; dichloromethane; mineral oil;
DOI:10.1021/acs.jmedchem.6b01482

Reference yield:

: 3433-37-2
piperidin-2-ylmethanol

: 220510-70-3
2-(phenoxymethyl)piperidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid; sodium tetrahydroborate / tetrahydrofuran / 0 - 20 °C

2.1: dmap; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

3.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere

3.2: 16 h / Inert atmosphere; Reflux

4.1: palladium 10% on activated carbon; hydrogen / methanol; dichloromethane / 16 h / 20 °C

With dmap; sodium tetrahydroborate; palladium 10% on activated carbon; hydrogen; sodium hydride; acetic acid; triethylamine; In tetrahydrofuran; methanol; dichloromethane; mineral oil;
DOI:10.1021/acs.jmedchem.6b01482