(S)-3-Cyclohex-1-enyl-4-ethyl-2,2-dimethyl-[1,3,2]oxazasilolidine

Base Information

• Chemical Name: (S)-3-Cyclohex-1-enyl-4-ethyl-2,2-dimethyl-[1,3,2]oxazasilolidine
• CAS No.: 101385-81-3
• Molecular Formula: C₁₂H₂₃NOSi
• Molecular Weight: 225.406
• Mol file: 101385-81-3.mol

Synonyms:

Chemical Property of (S)-3-Cyclohex-1-enyl-4-ethyl-2,2-dimethyl-[1,3,2]oxazasilolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-3-Cyclohex-1-enyl-4-ethyl-2,2-dimethyl-[1,3,2]oxazasilolidine

There total 2 articles about (S)-3-Cyclohex-1-enyl-4-ethyl-2,2-dimethyl-[1,3,2]oxazasilolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(dimethylamino)dimethylsilane (3768-58-9) + (S)-2-Cyclohexylideneamino-butan-1-ol → (S)-8-Ethyl-5,5-dimethyl-1,2,3,4,4a,5,7,8-octahydro-6-oxa-9-aza-5-sila-benzocycloheptene + (S)-3-Cyclohex-1-enyl-4-ethyl-2,2-dimethyl-[1,3,2]oxazasilolidine (101385-81-3)

Guidance literature:

With dimethylsilicon dichloride; In benzene; for 24h; Heating;

DOI:10.1016/0022-328X(85)87401-5

Reference yield:

dimethylsilicon dichloride (75-78-5,30107-43-8) + (S)-2,2-Dibutyl-3-cyclohex-1-enyl-4-ethyl-[1,3,2]oxazastannolidine → (S)-8-Ethyl-5,5-dimethyl-1,2,3,4,4a,5,7,8-octahydro-6-oxa-9-aza-5-sila-benzocycloheptene + (S)-3-Cyclohex-1-enyl-4-ethyl-2,2-dimethyl-[1,3,2]oxazasilolidine (101385-81-3)

Guidance literature:

for 2h; Title compound not separated from byproducts;

DOI:10.1016/0022-328X(85)87401-5

Reference yield:

acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) + (S)-8-Ethyl-5,5-dimethyl-1,2,3,4,4a,5,7,8-octahydro-6-oxa-9-aza-5-sila-benzocycloheptene + (S)-3-Cyclohex-1-enyl-4-ethyl-2,2-dimethyl-[1,3,2]oxazasilolidine (101385-81-3) → methyl 3-(2-oxocyclohexyl)propionate (10407-33-7,58769-44-1)

Guidance literature:

With potassium dihydrogenphosphate; dibutyltin chloride; Yield given. Multistep reaction; 1.) benzene, reflux, 24 h, 2.) ether, benzene, R_.T_., 2 h; enamine/imine ratio: 40/60;

DOI:10.1016/0022-328X(85)87401-5

upstream raw materials:

bis(dimethylamino)dimethylsilane

dimethylsilicon dichloride

Downstream raw materials:

methyl 3-(2-oxocyclohexyl)propionate