(1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-deoxy-6-[2-(4-nitrophenyl)-hydrazinyl]-d-glucitol

Base Information

• Chemical Name: (1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-deoxy-6-[2-(4-nitrophenyl)-hydrazinyl]-d-glucitol
• CAS No.: 1443356-84-0
• Molecular Formula: C₂₇H₃₀ClN₃O₇
• Molecular Weight: 544.004
• Mol file: 1443356-84-0.mol

Synonyms:

Chemical Property of (1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-deoxy-6-[2-(4-nitrophenyl)-hydrazinyl]-d-glucitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-deoxy-6-[2-(4-nitrophenyl)-hydrazinyl]-d-glucitol

There total 6 articles about (1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-deoxy-6-[2-(4-nitrophenyl)-hydrazinyl]-d-glucitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C27H29ClO9 (1443342-36-6) → (1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-deoxy-6-[2-(4-nitrophenyl)-hydrazinyl]-d-glucitol (1443356-84-0)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol / 2 h / 20 °C

2: lithium hydroxide; water / dichloromethane; methanol; tetrahydrofuran / 2 h / 0 °C

3: hydrogenchloride; sodium cyanoborohydride / methanol; water / 2 h / 0 °C / pH 1 - 3

With hydrogenchloride; water; sodium cyanoborohydride; lithium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; water;

DOI:10.1016/j.ejmech.2017.11.019

Reference yield:

C27H31ClO9 (1443341-94-3) → (1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-deoxy-6-[2-(4-nitrophenyl)-hydrazinyl]-d-glucitol (1443356-84-0)

Guidance literature:

Multi-step reaction with 4 steps

1: Dess-Martin periodane / chloroform-d1 / 3 h / 20 °C / Inert atmosphere

2: ethanol / 2 h / 20 °C

3: lithium hydroxide; water / dichloromethane; methanol; tetrahydrofuran / 2 h / 0 °C

4: hydrogenchloride; sodium cyanoborohydride / methanol; water / 2 h / 0 °C / pH 1 - 3

With hydrogenchloride; water; sodium cyanoborohydride; Dess-Martin periodane; lithium hydroxide; In tetrahydrofuran; methanol; chloroform-d1; ethanol; dichloromethane; water;

DOI:10.1016/j.ejmech.2017.11.019

Reference yield:

C33H34ClN3O10 → (1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-deoxy-6-[2-(4-nitrophenyl)-hydrazinyl]-d-glucitol (1443356-84-0)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium hydroxide; water / dichloromethane; methanol; tetrahydrofuran / 2 h / 0 °C

2: hydrogenchloride; sodium cyanoborohydride / methanol; water / 2 h / 0 °C / pH 1 - 3

With hydrogenchloride; water; sodium cyanoborohydride; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water;

DOI:10.1016/j.ejmech.2017.11.019

upstream raw materials:

C₂₇H₃₁ClO₉

C₂₇H₂₉ClO₉