Technology Process of 1-((3R)-1-{[(1R,3S)-aminocyclopentyl]carbonyl}-3-piperidinyl)-5-(methyloxy)-1-[2-(phenyloxy)phenyl]-1-pentanol trifluoroacetate
There total 1 articles about 1-((3R)-1-{[(1R,3S)-aminocyclopentyl]carbonyl}-3-piperidinyl)-5-(methyloxy)-1-[2-(phenyloxy)phenyl]-1-pentanol trifluoroacetate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 2 steps
1.1: benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.33 h / 20 °C
2.1: hydrogenchloride / water; acetonitrile / 16 h / 20 °C
2.2: pH 10
With
hydrogenchloride; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
water; N,N-dimethyl-formamide; acetonitrile;
