N-(N-{N-(L-arginyl)-[(2R,3S)-4-amino-2,3-difluorobutanoyl]}-L-aspartyl)-L-phenylalanine trifluoroacetic acid salt

Base Information

• Chemical Name: N-(N-{N-(L-arginyl)-[(2R,3S)-4-amino-2,3-difluorobutanoyl]}-L-aspartyl)-L-phenylalanine trifluoroacetic acid salt
• CAS No.: 1414874-30-8
• Molecular Formula: C₂HF₃O₂*C₂₃H₃₃F₂N₇O₇
• Molecular Weight: 671.578
• Mol file: 1414874-30-8.mol

Synonyms:

Chemical Property of N-(N-{N-(L-arginyl)-[(2R,3S)-4-amino-2,3-difluorobutanoyl]}-L-aspartyl)-L-phenylalanine trifluoroacetic acid salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(N-{N-(L-arginyl)-[(2R,3S)-4-amino-2,3-difluorobutanoyl]}-L-aspartyl)-L-phenylalanine trifluoroacetic acid salt

There total 1 articles about N-(N-{N-(L-arginyl)-[(2R,3S)-4-amino-2,3-difluorobutanoyl]}-L-aspartyl)-L-phenylalanine trifluoroacetic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H23N2O4Pol + (2R,3S)-4-{[((9H-fluoren-9-yl)methoxy)carbonyl]amino}-2,3-difluorobutanoic acid (1414874-25-1) + trifluoroacetic acid (76-05-1) + Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine (187618-60-6) → N-(N-{N-(L-arginyl)-[(Z)-4-amino-2-fluorobut-2-enoyl]}-L-aspartyl)-L-phenylalanine trifluoroacetic acid salt (1414874-28-4) + N-(N-{N-(L-arginyl)-[(2R,3S)-4-amino-2,3-difluorobutanoyl]}-L-aspartyl)-L-phenylalanine trifluoroacetic acid salt (1414874-30-8)

Guidance literature:

C₁₇H₂₃N₂O₄Pol; (2R,3S)-4-{[((9H-fluoren-9-yl)methoxy)carbonyl]amino}-2,3-difluorobutanoic acid; With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; In N,N-dimethyl-formamide; Wang resin

With piperidine; In N,N-dimethyl-formamide; Wang resin

trifluoroacetic acid; Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine; Further stages;

DOI:10.1039/c2ob26596f

upstream raw materials:

(2R,3S)-4-{[((9H-fluoren-9-yl)methoxy)carbonyl]amino}-2,3-difluorobutanoic acid

trifluoroacetic acid

Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine