3,4-Di-O-benzoyl-2,6-didesoxy-α-L-ribo-hexopyranosylchlorid

Base Information

• Chemical Name: 3,4-Di-O-benzoyl-2,6-didesoxy-α-L-ribo-hexopyranosylchlorid
• CAS No.: 106988-68-5
• Molecular Formula: C₂₀H₁₉ClO₅
• Molecular Weight: 374.821
• Mol file: 106988-68-5.mol

Synonyms:

Chemical Property of 3,4-Di-O-benzoyl-2,6-didesoxy-α-L-ribo-hexopyranosylchlorid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-Di-O-benzoyl-2,6-didesoxy-α-L-ribo-hexopyranosylchlorid

There total 3 articles about 3,4-Di-O-benzoyl-2,6-didesoxy-α-L-ribo-hexopyranosylchlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-Di-O-benzoyl-2,6-didesoxy-ξ-L-ribo-hexopyranose (106988-66-3,106988-67-4,117399-36-7,117399-48-1) → 3,4-Di-O-benzoyl-2,6-didesoxy-α-L-ribo-hexopyranosylchlorid (106988-68-5) + 1,5-Anhydro-3,4-di-O-benzoyl-2,6-didesoxy-L-ribo-hex-1-enit (107079-29-8)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; for 1h; Yields of byproduct given. Title compound not separated from byproducts;

Reference yield:

3,4-di-O-benzyl-2,6-dideoxy-D-ribo-hexopyranoside (106988-66-3,106988-67-4,117399-36-7,117399-48-1) → C20H19ClO5 (106988-68-5,117399-37-8,118605-57-5)

Guidance literature:

With molecular sieve; oxalyl dichloride; Multistep reaction; 1) DMF, CH₂Cl₂, 30 min, 2) RT;

DOI:10.1016/S0040-4020(01)97588-X

Reference yield:

methyl α-D-digitoxoside (102919-79-9) → C20H19ClO5 (106988-68-5,117399-37-8,118605-57-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / 50percent acetic acid / 6 h

2: 1) molecular sieves, 2) oxalyl chloride / 1) DMF, CH₂Cl₂, 30 min, 2) RT

With molecular sieve; oxalyl dichloride; acetic acid;

DOI:10.1016/S0040-4020(01)97588-X

upstream raw materials:

3,4-di-O-benzyl-2,6-dideoxy-D-ribo-hexopyranoside

methyl α-D-digitoxoside

3,4-Di-O-benzoyl-2,6-didesoxy-ξ-L-ribo-hexopyranose

Downstream raw materials:

methyl 4-O-(3,4-di-O-benzoyl-2,6-dideoxy-β-D-ribopyranosyl)-3-O-benzoyl-2,6-dideoxy-α-D-ribo-hexopyranoside

methyl 4-O-(3,4-di-O-benzoyl-2,6-dideoxy-α-D-ribopyranosyl)-3-O-benzoyl-2,6-dideoxy-α-D-ribo-hexopyranoside