(E)-3-(2-Chloro-phenyl)-3-phenyl-propenal

Base Information

• Chemical Name: (E)-3-(2-Chloro-phenyl)-3-phenyl-propenal
• CAS No.: 132118-11-7
• Molecular Formula: C₁₅H₁₁ClO
• Molecular Weight: 242.705
• Mol file: 132118-11-7.mol

Synonyms:

Chemical Property of (E)-3-(2-Chloro-phenyl)-3-phenyl-propenal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-(2-Chloro-phenyl)-3-phenyl-propenal

There total 2 articles about (E)-3-(2-Chloro-phenyl)-3-phenyl-propenal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

(-)-1-phenyl-1-(o-chlorophenyl)-2-propyn-1-ol (13732-87-1) → (Z)-3-(2-Chloro-phenyl)-3-phenyl-propenal (132118-12-8) + (E)-3-(2-Chloro-phenyl)-3-phenyl-propenal (132118-11-7)

Guidance literature:

With toluene-4-sulfonic acid; In solid; at 50 ℃; for 3h; Product distribution; other propargyl alcohol derivatives; other reaction time;

DOI:10.1039/c39900001270

Reference yield:

3-phenyl-propionaldehyde (104-53-0) + 2-iodochlorobenzene (615-41-8) → (Z)-3-(2-Chloro-phenyl)-3-phenyl-propenal (132118-12-8) + (E)-3-(2-Chloro-phenyl)-3-phenyl-propenal (132118-11-7)

Guidance literature:

With oxygen; palladium diacetate; acetic acid; silver carbonate; at 100 ℃; for 10h; Overall yield = 34 %; Optical yield = 65.517 %de; Sealed tube;

DOI:10.1002/ejoc.201701025

upstream raw materials:

(-)-1-phenyl-1-(o-chlorophenyl)-2-propyn-1-ol

3-phenyl-propionaldehyde

2-iodochlorobenzene