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Technology Process of 5′-O-(4,4-dimethoxytrityl)-2′-O-(tert-butyldimethylsilyl)-N2-phenoxyacetylguanosine 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl)phosphorothioamidite

5′-O-(4,4-dimethoxytrityl)-2′-O-(tert-butyldimethylsilyl)-N2-phenoxyacetylguanosine 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl)phosphorothioamidite

Base Information
  • Chemical Name:5′-O-(4,4-dimethoxytrityl)-2′-O-(tert-butyldimethylsilyl)-N2-phenoxyacetylguanosine 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl)phosphorothioamidite
  • CAS No.:1404222-91-8
  • Molecular Formula:C54H61Cl2N6O9PSSi
  • Molecular Weight:1100.14
  • Hs Code.:
5′-O-(4,4-dimethoxytrityl)-2′-O-(tert-butyldimethylsilyl)-N<sup>2</sup>-phenoxyacetylguanosine 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl)phosphorothioamidite

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Chemical Property of 5′-O-(4,4-dimethoxytrityl)-2′-O-(tert-butyldimethylsilyl)-N2-phenoxyacetylguanosine 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl)phosphorothioamidite
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Technology Process of 5′-O-(4,4-dimethoxytrityl)-2′-O-(tert-butyldimethylsilyl)-N2-phenoxyacetylguanosine 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl)phosphorothioamidite

There total 1 articles about 5′-O-(4,4-dimethoxytrityl)-2′-O-(tert-butyldimethylsilyl)-N2-phenoxyacetylguanosine 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl)phosphorothioamidite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C<sub>48</sub>H<sub>62</sub>N<sub>5</sub>O<sub>9</sub>PSi

C48H62N5O9PSi

2,4-dichlorobenzyl mercaptan
59293-67-3

2,4-dichlorobenzyl mercaptan

5′-O-(4,4-dimethoxytrityl)-2′-O-(tert-butyldimethylsilyl)-N<sup>2</sup>-phenoxyacetylguanosine 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl)phosphorothioamidite
1404222-91-8,1404222-92-9

5′-O-(4,4-dimethoxytrityl)-2′-O-(tert-butyldimethylsilyl)-N2-phenoxyacetylguanosine 3′-N,N-dimethyl-S-(2,4-dichlorobenzyl)phosphorothioamidite

Guidance literature:
In acetonitrile; at 20 ℃; for 0.5h;
DOI:10.1021/jo301834p
upstream raw materials:

2,4-dichlorobenzyl mercaptan

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