2,10-Dihydro-10-oxo-2-phenyl[1,2]oxazino[3,2-b]quinazoline-4-carboxaldehyde

Base Information

Chemical Name:2,10-Dihydro-10-oxo-2-phenyl[1,2]oxazino[3,2-b]quinazoline-4-carboxaldehyde
CAS No.:107400-09-9
Molecular Formula:C₁₈H₁₂N₂O₃
Molecular Weight:304.305
Hs Code.:
DSSTox Substance ID:DTXSID301143210

Synonyms:DTXSID301143210;2,10-Dihydro-10-oxo-2-phenyl[1,2]oxazino[3,2-b]quinazoline-4-carboxaldehyde;107400-09-9

Suppliers and Price of 2,10-Dihydro-10-oxo-2-phenyl[1,2]oxazino[3,2-b]quinazoline-4-carboxaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,10-Dihydro-10-oxo-2-phenyl[1,2]oxazino[3,2-b]quinazoline-4-carboxaldehyde

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:304.08479225
Heavy Atom Count:23
Complexity:563

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2C=C(C3=NC4=CC=CC=C4C(=O)N3O2)C=O

Technology Process of 2,10-Dihydro-10-oxo-2-phenyl[1,2]oxazino[3,2-b]quinazoline-4-carboxaldehyde

There total 3 articles about 2,10-Dihydro-10-oxo-2-phenyl[1,2]oxazino[3,2-b]quinazoline-4-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 2-(3-benzyloxy-4-oxoquinazolinyl)malondialdehyde

: 107400-09-9
4-formyl-2-phenyl<1,2>oxazino<3,2-b>quinazol-10-one

Guidance literature:: With pyridine; hydrogen bromide; Ambient temperature;

Reference yield:

: 107400-07-7
(Z)-2-(3-Benzyloxy-4-oxo-3,4-dihydro-quinazolin-2-yl)-3-dimethylamino-propenal

: 107400-09-9
4-formyl-2-phenyl<1,2>oxazino<3,2-b>quinazol-10-one

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / 5percent aq. NaOH / 0.5 h / 80 °C

2: 30 percent / pyridine, 40percent aq. HBr / Ambient temperature

With pyridine; sodium hydroxide; hydrogen bromide;

Reference yield:

: 4765-41-7
3-benzyloxy-2-methyl-4-quinazolone

: 107400-09-9
4-formyl-2-phenyl<1,2>oxazino<3,2-b>quinazol-10-one

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / POCl₃ / 5 h / 70 - 75 °C

2: 90 percent / 5percent aq. NaOH / 0.5 h / 80 °C

3: 30 percent / pyridine, 40percent aq. HBr / Ambient temperature

With pyridine; sodium hydroxide; hydrogen bromide; trichlorophosphate;